374 



Dr. C. H. Jones on the Effects of Exercise [June 19, 



Experiment X. 



November 28t7i, 1872. — One fifth of a drop of cobra-poison (the first 

 supply), diluted with about 2 cub. centims. of | per cent, salt, was injected 

 into the external jugular of a rabbit. 



12.5. Injection made. 



12.20. The animal has been convulsed and paralyzed. Sensibility of 

 the cornea has disappeared ; cannula placed in trachea and artificial re- 

 spiration commenced. Temperature 100°. 



1.15. Temperature 96°-3. Heart is beating vigorously. 



3.13. Heart is beating as before. 



3.20. In order to try if possible to quicken ehmination milk was in- 

 jected into the stomach. 



4.5. Heart is beating as well as ever. 



4.40. Heart still beating vigorously. Respiration discontinued. Death 

 soon followed. In this case also life was prolonged by artificial respira- 

 tion. 



III. cc Observations on the Effects of Exercise on the Temperature 

 and Circulation." By C. Handfield Jones, M.B. Cantab., 

 F.R.S. Received May 24, 1873. 



The effects of nervo-muscular exertion on the great functions of circu- 

 lation and calorification in the human body must always form an inter- 

 esting subject of observation, not only to the physiologist, but also to the 

 physician, as affording the best available test of the power of the indi- 

 vidual frame to endure the strain of disease as well as of fatigue. The 

 effect of bodily exertion on temperature has often been observed. J. 

 Davy found active exertion to raise the temperature l 0, 7 E. Obernier found 

 that a quick march of 1 j hour raised the temperature 1°'8 to 2°*16E. Wun- 

 derlich gives the case of an athlete, who, while running a race, suddenly 

 became faint and insensible, and was found soon after to have a tempera- 

 ture of 104°*9 E., a pulse of 128, and some albumen in his. urine. In two 

 hours the temperature had fallen to 102 o, 38. On the second morning the 

 temperature was normal, and remained so, while the urine quickly became 

 free from albumen. Dr. Bathurst Woodman relates the case of a youth 

 who, after walking seventy miles in two days, had a temperature of 105° E., 

 with a pulse of 130, and enormous quantities of lithates in the urine. 

 Another, after similar exertion, was similarly affected. This evidence seems 

 conclusive as to the tendency of severe nervo-muscular exertion to raise the 

 bodily temperature ; and it seems that this result is promoted by any 

 existing debility, as in one of Obernier's observations, when the man was 

 out of health, a very fast walk of one hour raised his temperature to 

 103°-28 E. Wunderlich's and Dr. Woodman's cases are of special interest, 



