1871.] History of the Opium Alkaloids, 15 



formed by the action of hydriodic acid on codeia at about 130°, a 

 substance similar in characters to that got from the other two compounds 

 is produced. The final product, however, differs somewhat in its physical 

 characters from those just mentioned ; instead of coming out from the hot 

 aqueous solution in solid flakes, it appears in very minute solid oil-globules 

 which do not readily subside, and give to the liquid a great resemblance to 

 fresh milk ; sometimes the globules do not subside for many days. 



Dried at 100° these globules give numbers indicating a compound ana- 

 logous to that of the non-iodized base just described ; it is, however, much 

 more difficult in this instance to remove the last portions of basic HI ; 

 moreover, four molecules of water appear to be taken up, probably in lieu 

 of the oxygen lost. 



Specimen A. Original substance treated three times with large excess 

 of water : — 



0-3315 grm. gave 0*589 C0 2 and 0*175 H 2 O. 



0*299 grm. gave 0*178 Ag I. 



Specimen B. Original with water four times : — 



321 grm. gave 0-585 C0 2 and 0169 H 2 0. 



0-411 grm. gave 0754 C0 2 and 0-218 H 2 0. 



0-2835 grm. gave 0*165 Agl. 



Specimen C. Original with water five times : — 



0-4095 grm. gave 0*746 C0 2 and 0*219 H 2 0. 



0*3995 grm. gave 0*237 Agl. 



Found. 





Calculated. 



A. B. C. 



C 68 



816 



50*00 



, * ; 



48-46 49*71 50*03 49*68 





92 



5-64 



5*87 5*85 5-89 5-94 





508 



31*13 



32*17 31*45 32-06 



N 4 



56 



3*43 





o,„ 



160 



9*80 





C M H M N 4 O 10) 4HI 



1632 



100-00 





Mean. 

 49-47 

 5-89 

 31-89 



Hence this compound is formed by the reaction 



C 68 H 82 I 2 N 4 6 , 4HI + 4H 2 O = 2HI + C n8 H 88 N 4 O 10 , 4 HI. 



Carbonate of soda threw down from specimen C a white precipitate, 

 becoming yellow on standing : this precipitate contained a small amount 

 of iodine, showing (as the above numbers indicate) that the transformation 

 of the original substance was not absolutely complete. 



The qualitative reactions of this substance are the same as those of the 

 bodies previously described. 



§ 3. Action of Sodium Carbonate on the compound 

 68 H 86 I 2 N 4 O 12 ,4HI, 

 On adding sodium carbonate to the scarcely warm aqueous solution of 



