280 Dr. C. R. A. Wright's Contributions to the [Apr. 11, 



Found. 



Calculated. , * N 



, « s A. B. 



C 1U 1728 64-38 64-87 63-48 



H J7C 176 6-56 6-36 6*54 



N 8 ' 112 4-17 



24 384 14-30 



Cl 8 284 10-59 10-08 



C lw H 1M N 8 O al , 8H CI 2684 100-00 



The free base gave the following numbers : — 



0-3095 grm. gave 0'818CO 2 and 0-190 H 2 0. 



Calculated. Found. 



C m 172S 72-24 72-08 



H ie8 168 7-02 6-82 



N 8 112 4-68 



01 384 16-06 



C ]44 H 1GS N 8 24 2392 100-00 



In appearance and most physical properties, tetracodeia and its salts bear 

 a great resemblance to chloro- and bromo-tetracodeia ; and they further 

 agree in that all yield a blood-red colour on warming with silver nitrate 

 and nitric acid, or with nitric acid alone ; it differs from chloro-tetracodeia 

 in that the aqueous solution of the hydrochlorate does not precipitate on the 

 addition of strong H CI, the salt being apparently as soluble in diluted H CI 

 as in water ; also the free base does not oxidize so readily. In all respects 

 tetracodeia agrees with the description given by Anderson of his " amor- 

 phous codeia"* obtained by the action of sulphuric acid on codeia. 

 On comparison with the. product obtained by Anderson's process, no essen- 

 tial differences could be detected between the two substances, except that 

 the phosphoric-acid product was somewhat darker in tint, owing no doubt 

 to the presence of colouring-matters from the higher temperature employed 

 in its production. 



The hydrochlorate of dicodeia obtained as above described crystallizes 

 with 3H 2 O for every C 18 contained, this water of crystallization being 

 wholly lost at 100° and partially by standing over sulphuric acid. 



2-163 grms. of crystals dried on filter-paper lost at 100° 0*295 grm. 



Actual loss = 13-63 per cent. 



Calculated for C 72 II 84 N 4 12 , 4HCI + 12H a 0=13-86 „ 



2 012 grms. of crystals that had stood three days 1 R ~ . 



over S0 4 H 2 lost, at 100°, 0-172 J ~ " 



* Anderson,, Ed. Phil, Trans, xx. [1] 57; 



