1872.] History of the Opium Alkaloids, 283 



Calculated. 



✓ * s Found. 



C 108 1296 68*03 67*16 



H 120 120 6-30 6-69 



Cl 6 213 11-18 11-48 



N 6 . 84 4-41 



12 192 HH)8 



C 108 H m N c 13 , 6HC1 1905 100-00 



Hence this product has been formed by the reaction 



C 103 H 120 N C 0,„ 6HC1= 6H 2 + C 108 H U4 N c I2 , 6HC1, 

 and has the composition of a polymeride of "apocodeia." From the great 

 similarity observed between this product and "apocodeia" made by Mat- 

 thiessen and Burnside's process*, it appears probable that the product of 

 the action of zinc chloride on codeia is a mixture of bodies of general for- 

 mula (C 18 N 19 N0 2 ) TO , wHCl, in which the derivative where n=6 greatly 

 predominates : experiments on the action of zinc chloride on morphia now 

 in progress in conjunction with Herr L. Mayer indicate that mixtures are 

 obtained in this case also. 



(c) Bicodeia. — When pure dicodeia hydrochlorate is heated to 100° for 

 one hour with a large excess of HC1, a change is produced expressible by 

 the equation 



C 72 H 84 N 4 12 , 4HCl + HCl=C 7a H 83 CI N 4 O n , 4HC1 + H 2 O, 

 which shows that the formula of this polymeride contains at least C 72 . 

 Na 2 C0 3 throws down from the product a voluminous white precipitate, 

 which differs in appearance slightly from that of dicodeia and turns green 

 by exposure to air ; ether dissolves this precipitate, and on agitation with 

 HC1 a viscid hydrochlorate is obtained which does not crystallize, but dries 

 up to a gum. Fe 2 Cl 6 gives a brown-purple tint, N0 3 H a blood*red, and 

 K 2 Cr 2 7 +SO i H 2 a lighter blood-red, none of which reactions occur with 

 the original dicodeia. Dried at 100°, 



0-3200 grm. gave 0737 C0 2 and 0*189 H 2 0. 



0-3260 „ 0-172 AgCl. 



Calculated. 



, A Found. 



C 72 864 63-50 62-82 



H 87 87 6-39 6-56 



Cl 5 177*5 13-04 15-06 



N 4 56 4-12 



Q» . . J 76 2 2 ^- r) 



C 7a H 83 ClN 4 O u , 4HC1 1360-5 100-00 



* Proc. Roy. Soc. vol. xix. p. 71. 



