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drcds, from one year old upwards, with 

 the moll happy fuccefsj the patients, 

 after the fecond dofe, ufually difcharg- 

 ing an incredible number of Worms, 

 even to the amount of more than twen- 

 ty at a time, fo that the ftools confifted 

 of little elfe than thefe animals. But 

 though thefe were indifputable proofs 

 of its efficacy, I was far from being con- 

 vinced of its fafety. I obferved, that 

 the fubftance given confifted of an af- 

 femblage of fpiculae, exquifitely fine, 

 and fo acutely pointed, that when ap- 

 plied to the fkin they excited an intole- 

 rable itching, and even inflammation, 

 from whence I apprehended dangerous 

 confequences from their contact with 

 the coats of the ftomach and inteftines. 

 Indeed, when mixed into an ele&uary, 

 in the manner in which they are given, 

 their elafticity is fo impaired, that they 

 do not produce the fame fenfible irrita- 

 tion j but yet I could conceive no other 



quality 



