1878.] the Poisonous Principle of Urechites Suberecta. 317 



July 12th, 14th, 15th, 16th, during which time its weight fell to 

 5 lbs. 



For the last few days it was rather dull and inactive, and lost its 

 appetite. 



At 10 a.m., on July 17th, there was nothing to attract notice in its 

 appearance ; but at 11 o'clock it was seized with convulsions, passed 

 faeces involuntarily ; and after the convulsions passed off it lay on its 

 side breathing heavily from the abdomen till about 1 p.m., when it died 

 in a second attack of convulsions. 



Its bladder was found distended with urine, the stomach and intes- 

 tines empty and tense, the latter almost wiry. Gall-bladder full, 

 liver very dark and full of blood. All the veins full of dark blood, 

 which coagulated very quickly. Lungs pale. Heart, right side 

 gorged with dark blood, left side contained a little redder blood, but 

 not fully aerated. Arteries collapsed, and nearly empty. Pupils dis- 

 tended so as almost to obliterate iris. Tongue bluish immediately 

 after death. 



Experiment XIY. 



A white cat, weighing 6 lbs. at the beginning of the experiment, 

 was treated exactly as the one in Experiment XIII, a square of paper 

 containing 10 1 00 gr. of urechitoxin being given to it every week day 

 (with one exception) for eleven weeks. Its weight gradually increased, 

 so that it weighed lbs. at the end of that time. No effect was 

 apparent up to the day on which it received the last dose. In the 

 morning it was well and cheerful, at 1 p.m. it was discovered very ill, 

 possibly it had been attacked by convulsions. However, it took the 

 dose of poison, and ate a little food. Next day it seemed well, no 

 poison was given to it. The day after it died about 10 a.m. ; it was 

 not seen to die, but it presented the appearances seen in other cats 

 poisoned with urechitoxin. There had been a little purging shortly 

 before death. 



Experiment XV. 



A kitten, weighing If lbs., was treated in the same manner as the 

 cats in Experiments XIII and XIV, a square of poisoned paper being 

 given to it every week day for nearly four weeks, a total of 22 doses 

 being administered. For the first three weeks no effect was apparent 

 and its weight increased to 2 lbs. ; during the last week it appeared 

 dull and did not care for its food, its weight falling to 1J lbs. 1 There 

 was nothing calling for special note in its mode of death or in the 

 appearances subsequently observed. 



Exp. XIII. Dose two" g r -> 11 given, total weight of poison ex- 

 hibited -^y gr. = 071 mgm. Weight of cat 5J lbs., fell to 5 lbs. 



t 2 



