1878.] on Destroying the Activity of Cobra Poison. 467 



3.52 p.m. The same state. 



3.58 „ Defecating. Micturating. 



3.59 „ Retching. Vomiting. Moves about in a restless manner. 

 4.6 „ Moving backwards with staggering gait. 



4.12 ,, Staggers, and head droops. 



4.13 „ Falls over on its side. The respiration is slow. Reflex 

 from eye and ear almost gone. 



4.14 p.m. Reflex from head and legs when irritated. None from 

 tail. 



4.15 „ Attempts to rise. 



4.18 Got up, but fell over again. Tried to walk. No reflex 

 from the head. 



4.20 p.m. Head raised and fell over again. Touching the eye seems 

 to rouse the cat, but no reflex of lids. Tries to get up, but cannot. 

 Fell over on the opposite side. 



4.24 p.m. Again a struggle to rise. 



4.27 „ Touching the eye produces no reflex. Breathing very slow. 

 Convulsive twitching of limbs. 



4.28 p.m. Apparently dead. Heart still beating one hour and two 

 minutes after injection of poison. 



The blood, after death, formed a firm coagulum. 



Intestines much congested. Patch of congestion in stomach. Red 

 serum effused into the peritoneal cavity. 

 ~No local symptoms or changes. 



A good deal of food in the stomach, notwithstanding the vomiting. 

 Digestion was in full action. 



In these and other experiments the dose of cobra poison was regu- 

 lated according to the weight of the animal, the same proportion per 

 pound weight being given in each case. 



Experiment III. 



A grey cat 4 lbs. weight had 20 mgms. of cobra poison, dissolved in 

 one cub. centim. of distilled water, injected under skin of flank at 

 3.39 p.m. of 25th February. 



At 3.40 p.m. a solution of chloride of platinum injected at the same 

 spot. 



3.42 p.m. Very restless. 



3.43 Drinks water. 

 3.52 „ Vomiting. 



3.55 „ Dull and depressed. 



4.10 „ Same condition. 



4.20 „ Sluggish. 



4.30 ,, Restless. Moving about. 



4.45 „ Staggers. Getting very sluggish. Walks with difficulty. 

 Head drooping. 



