468 



Dr. T. L. Brunton and Sir J. Fayrer [June -20, 



4.54 p.m. Shivering. Head fallen over. 



5 p.m. Fallen over. Slow paralysis creeping over limbs. Respira- 

 tion slow. Gets up, rolls over again. On touching the eye the eyelid 

 moves. Reflex not gone from the ear. 



5.6 p.m. Fallen over. Paralysed. Reflex nearly gone, still slight 

 from ear. Pupils dilated. 



5.9 p.m. Convulsions. Pupils become normal again. Respiration 

 very slow — thirteen per minute. 



5.20 p.m. Tries to rise. Very feebly. 



5.22 ,, Fallen quite over. 



5.23 ,, In same condition. Makes feeble efforts to rise. Pupils 

 dilated again. 



5.27 p.m. Again tries to rise. Micturition. 



5.29 ,, Convulsions. 



5.30 „ Dead. 



~No local symptoms, i.e., no extravasation about the puncture. No 

 congestion of stomach or bowels. Stomach empty. Blood coagulated 

 after death. 



■ Injected at 3.39 p.m. 

 Died at 5.30 p.m. 



Death in one hour and fifty-one minutes. 



The following experiments show the effect of chloride of gold in 

 completely destroying the cobra poison. 



Experiment IV. 



March 7th, 1878. Three mgms. of cobra poison, mixed with 1 

 grain of chloride of gold, dissolved in 40 grain measures of water, 

 injected into the hip of a white guinea-pig, weighing 18 oz., at 3.50 p.m. 



4.10 p.m. Crouching quietly in corner of box. Tremor, perhaps 

 fright. 



4*15 p.m. Seems uneasy ; crouching in corner. No other change. 

 Recovered without any bad symptoms. 



Experiment V. 



March 14th. In this experiment a very large dose of poison was 

 used. 



30 mgms. of cobra poison, mixed with 1^- cub. centims. of a 10 per 

 cent, solution of chloride of gold, were injected into a guinea-pig 

 weighing 20 oz., at 3.30 p.m. 



75 cub. centims. of water was used to wash out glass, and then 

 injected. The poison and the chloride form a yellow creamy precipi- 

 tate. 



3.30 p.m. Began to jerk and twitch immediately, excited, running 

 about the box. 



3.35 p.m. Crouching in corner, twitching, but not otherwise affected. 



