﻿1875.] 
  

  

  Action 
  of 
  the 
  Crotalus-poison, 
  fyc. 
  

  

  265 
  

  

  12.20. 
  Twitchings 
  much 
  increased, 
  now 
  mainly 
  in 
  head 
  and 
  neck, 
  not 
  

   so 
  much 
  in 
  hind 
  legs. 
  

  

  12.28. 
  Guineapig 
  quiet, 
  but 
  with 
  occasional 
  twitchings 
  ; 
  sluggish 
  and 
  

   disinclined 
  to 
  move. 
  

  

  1.30. 
  Sluggish 
  in 
  moving 
  ; 
  can 
  still 
  move 
  about, 
  though 
  disinclined 
  to 
  

   do 
  so. 
  The 
  punctured 
  thigh 
  is 
  very 
  blue. 
  

  

  The 
  rest 
  of 
  the 
  notes 
  of 
  this 
  experiment 
  were 
  lost. 
  

  

  The 
  animal 
  died. 
  

  

  Experiment 
  III. 
  

  

  June 
  10^, 
  1874. 
  — 
  | 
  of 
  a 
  grain 
  of 
  Crotalus- 
  and 
  | 
  of 
  a 
  grain 
  of 
  cobra- 
  

   poison 
  were 
  carefully 
  weighed 
  and 
  diluted, 
  each 
  with 
  ten 
  drops 
  of 
  dis- 
  

   tilled 
  water. 
  Two 
  full-grown 
  guineapigs 
  of 
  equal 
  weight 
  were 
  then 
  

   selected. 
  

  

  The 
  solution 
  of 
  Crotalus--poisoB. 
  was 
  injected 
  into 
  the 
  peritoneal 
  cavity 
  

   of 
  guineapig 
  No. 
  1 
  at 
  1.52 
  p.m. 
  

  

  1.55. 
  Muscular 
  twitchings 
  of 
  head 
  and 
  neck. 
  

   2 
  p.m. 
  Startings 
  and 
  twitchings 
  continue. 
  

  

  It 
  gives 
  faint 
  squeaks 
  occasionally, 
  as 
  though 
  the 
  sudden 
  startings 
  

   which 
  occur 
  at 
  intervals 
  of 
  5 
  or 
  6 
  seconds 
  cause 
  pain. 
  

   2.5. 
  Twitchings 
  continue. 
  

  

  2.8. 
  Very 
  restless 
  ; 
  twitchings 
  going 
  on, 
  but 
  no 
  paralysis 
  yet. 
  

   2.17. 
  The 
  same. 
  

  

  2.25. 
  Eestless 
  and 
  weaker 
  ; 
  but 
  still 
  moves 
  freely 
  on 
  being 
  roused. 
  

   2.42. 
  Sluggish 
  ; 
  drags 
  the 
  hind 
  legs. 
  

  

  2.58. 
  "Weaker; 
  rolls 
  partially 
  over 
  on 
  one 
  side, 
  but 
  can 
  run 
  when 
  

   roused. 
  

  

  3.3. 
  Lying 
  on 
  side, 
  but 
  can 
  be 
  roused 
  ; 
  is 
  partially 
  paralyzed 
  in 
  

   hind 
  legs. 
  Eespiration 
  abdominal 
  and 
  hurried. 
  

  

  3.5. 
  Nearly 
  quite 
  paralyzed; 
  is 
  roused 
  with 
  difficulty. 
  

  

  3.7. 
  Can 
  still 
  be 
  roused. 
  Abdomen 
  distended 
  and 
  painful 
  ; 
  cries 
  out 
  

   when 
  it 
  is 
  touched, 
  as 
  though 
  peritonitis 
  were 
  setting 
  in. 
  

  

  3.12. 
  Can 
  be 
  roused 
  with 
  difficulty 
  ; 
  respiration 
  hurried 
  ; 
  convulsive 
  

   movements 
  of 
  fore 
  legs 
  and 
  neck. 
  Can 
  still 
  stagger 
  for 
  a 
  few 
  paces 
  ; 
  but 
  

   coordination 
  of 
  muscular 
  power 
  much 
  diminished, 
  

  

  3.30. 
  In 
  violent 
  convulsions. 
  

  

  3.38. 
  Convulsions 
  continue. 
  

  

  3.45. 
  Quiet. 
  Paralyzed 
  ; 
  but 
  reflex 
  action 
  still 
  continues. 
  

  

  3.55. 
  Dead 
  in 
  2 
  hours 
  and 
  3 
  minutes. 
  

  

  3.56. 
  Electrodes 
  in 
  cord 
  cause 
  twitching 
  of 
  muscles 
  of 
  the 
  back, 
  and 
  

   very 
  slightly 
  in 
  those 
  of 
  the 
  legs 
  : 
  the 
  cord 
  was 
  evidently 
  all 
  but 
  para- 
  

   lyzed. 
  Muscular 
  fibre 
  contracts 
  freely 
  to 
  direct 
  stimulus 
  of 
  current. 
  The 
  

   intestines 
  were 
  ecchymosed 
  and 
  congested. 
  There 
  were 
  effusions 
  of 
  red 
  

   serum 
  into 
  the 
  peritoneal 
  cavity, 
  and 
  much 
  ecchymosis 
  of 
  peritoneum 
  

   and 
  subperitoneal 
  and 
  intra-muscular 
  areolar 
  tissue. 
  Peristaltic 
  action 
  

   continued 
  faintly. 
  

  

  VOL, 
  XXIII, 
  X 
  

  

  