﻿266 
  Drs. 
  Brunton 
  and 
  Fayrer 
  on 
  the 
  Physiological 
  [Feb. 
  18, 
  

  

  4 
  p.m. 
  The 
  heart 
  has 
  ceased 
  to 
  contract 
  4 
  minutes 
  after 
  apparent 
  death 
  ; 
  

   it 
  continued 
  to 
  contract, 
  especially 
  the 
  auricles, 
  for 
  part 
  (not 
  the 
  whole) 
  

   of 
  the 
  time. 
  

  

  The 
  blood 
  removed 
  from 
  the 
  heart-cavities 
  and 
  vena 
  cava 
  rapidly 
  

   formed 
  a 
  firm 
  coagulum 
  in 
  a 
  glass 
  receiver. 
  

  

  The 
  electrodes 
  applied 
  to 
  the 
  sciatic 
  showed 
  that 
  the 
  nerve-trunk, 
  as 
  

   well 
  as 
  the 
  spinal 
  cord, 
  was 
  paralyzed. 
  

  

  Experiment 
  IV. 
  

  

  Guineapig 
  No. 
  2, 
  an 
  albino, 
  had 
  the 
  |-grain 
  cobra- 
  virus 
  solution 
  injected 
  

   into 
  its 
  peritoneal 
  cavity 
  at 
  1.56 
  p.m. 
  

   It 
  immediately 
  became 
  much. 
  excited. 
  

   1.57. 
  Is 
  now 
  quite 
  tranquil. 
  

  

  2. 
  Sluggish. 
  Does 
  not 
  twitch 
  as 
  guineapig 
  Ko. 
  1 
  did. 
  

  

  2.4. 
  Started 
  and 
  squeaked 
  slightly, 
  as 
  though 
  in 
  pain, 
  but 
  no 
  twitching. 
  

  

  2.5. 
  Slight 
  twitching 
  generally. 
  Paralysis 
  and 
  ataxy 
  commencing; 
  

   drags 
  its 
  legs 
  with 
  difficulty. 
  

  

  2.9. 
  Sharp 
  twitchings 
  of 
  head 
  and 
  neck. 
  

  

  2.12. 
  Subsided 
  on 
  to 
  the 
  belly 
  ; 
  head 
  fallen 
  over 
  ' 
  x 
  crawls 
  with 
  diffi- 
  

   culty 
  ; 
  is 
  very 
  feeble, 
  almost 
  paralyzed. 
  The 
  albino 
  eyes 
  have 
  a 
  heavy 
  

   dull 
  look 
  ; 
  lost 
  their 
  bright 
  pink. 
  

  

  2.14. 
  Convulsed. 
  

  

  2.15. 
  Keflex 
  action 
  ceased. 
  Apparently 
  dead, 
  but 
  heart 
  can 
  still 
  be 
  

   felt 
  beating. 
  Occasional 
  convulsive 
  twitchings 
  of 
  lower 
  lip. 
  

  

  2.16. 
  Dead 
  in 
  21 
  minutes. 
  

  

  2.17. 
  All 
  movements 
  have 
  ceased. 
  Heart 
  had 
  ceased 
  to 
  contract, 
  

   except 
  slight 
  flickering 
  movements 
  of 
  auricles. 
  

  

  2.20. 
  Electrodes 
  in 
  cord. 
  Spinal 
  cord 
  and 
  nerves 
  paralyzed 
  ; 
  muscles 
  

   contract 
  freely 
  to 
  direct 
  stimulus 
  of 
  current. 
  Heart 
  distended 
  with 
  

   blood. 
  Blood, 
  when 
  removed, 
  formed 
  rapidly 
  a 
  firm 
  coagulum. 
  Intes- 
  

   tines, 
  peritoneum, 
  and 
  subperitoneal 
  areolar 
  tissue 
  congested 
  and 
  ecchy- 
  

   mosed. 
  Sanguinolent 
  effusions 
  into 
  peritoneum, 
  but 
  not 
  so 
  well 
  marked 
  

   as 
  in 
  the 
  CrotoZ«s-poisoning. 
  Peristaltic 
  action 
  of 
  bowels 
  ceased 
  

   rapidly. 
  

  

  The 
  results 
  of 
  these 
  two 
  experiments 
  show, 
  so 
  far, 
  that 
  the 
  action 
  of 
  

   the 
  cobra-poison 
  is 
  more 
  energetic 
  than 
  that 
  of 
  the 
  rattlesnake. 
  Both 
  

   were 
  watery 
  solutions 
  of 
  exactly 
  the 
  same 
  quantity 
  of 
  the 
  dried 
  virus 
  ; 
  

   but 
  it 
  is 
  to 
  be 
  borne 
  in 
  mind 
  that 
  that 
  of 
  the 
  rattlesnake 
  was 
  6| 
  years 
  

   old, 
  while 
  that 
  of 
  the 
  cobra 
  was 
  only 
  one 
  year 
  old. 
  

  

  The 
  guineapigs 
  were 
  both 
  full-grown 
  and 
  of 
  the 
  same 
  size 
  ; 
  yet 
  one 
  

   succumbed 
  in 
  20 
  minutes 
  to 
  the 
  cobra-poison, 
  while 
  the 
  other 
  survived 
  

   the 
  inoculation 
  of 
  the 
  rattlesnake-poison 
  for 
  2 
  hours 
  and 
  3 
  minutes. 
  

  

  There 
  were 
  no 
  very 
  marked 
  differences 
  in 
  the 
  action 
  of 
  the 
  poison 
  in 
  

  

  