﻿238 
  Drs. 
  Bmnton 
  and 
  Fayrer 
  on 
  the 
  Physiological 
  [Feb. 
  18, 
  

  

  caused 
  by 
  rapid 
  paralysis 
  of 
  medulla 
  and 
  cord. 
  The 
  blood 
  taken 
  from 
  

   the 
  heart 
  and 
  great 
  vessels 
  did 
  not 
  coagulate. 
  At 
  4 
  p.m. 
  it 
  was 
  still 
  

   fluid, 
  though 
  very 
  florid 
  in 
  colour. 
  

  

  Examined 
  under 
  the 
  microscope 
  nearly 
  2 
  hours 
  after 
  apparent 
  death, 
  

   the 
  white 
  corpuscles 
  appeared 
  natural; 
  the 
  red 
  corpuscles 
  not 
  in 
  

   rouleaux, 
  and 
  very 
  much 
  crenated, 
  though 
  a 
  few 
  retained 
  their 
  natural 
  

   contour. 
  

  

  The 
  blood 
  was 
  natural 
  to 
  test-paper. 
  

  

  Experiment 
  VII. 
  

  

  Jane 
  17th. 
  — 
  | 
  of 
  a 
  grain 
  (*015 
  gramme) 
  of 
  dried 
  cobra-poison, 
  dissolved 
  

   in 
  1 
  cub. 
  centim. 
  of 
  water, 
  was 
  injected 
  into 
  the 
  jugular 
  vein 
  of 
  a 
  large 
  

   white 
  rabbit, 
  of 
  the 
  same 
  size 
  as 
  in 
  the 
  previous 
  experiment, 
  at 
  2.55 
  p.m. 
  

  

  The 
  rabbit 
  passed 
  at 
  once 
  into 
  violent 
  convulsions, 
  and 
  was 
  apparently 
  

   dead 
  before 
  it 
  could 
  be 
  removed 
  from 
  the 
  board, 
  within 
  one 
  minute. 
  The 
  

   cord 
  was 
  immediately 
  exposed, 
  artificial 
  respiration 
  having 
  also 
  been 
  

   begun. 
  Electrodes 
  applied, 
  with 
  strong 
  current 
  ; 
  no 
  reaction 
  ; 
  the 
  cord 
  

   was 
  perfectly 
  paralyzed. 
  

  

  Thorax 
  examined 
  at 
  2.59. 
  Heart 
  had 
  ceased 
  to 
  contract. 
  Ventricles 
  

   moderately 
  contracted. 
  Auricles 
  distended 
  with 
  blood. 
  Phrenic 
  irri- 
  

   tated, 
  quite 
  paralyzed. 
  Diaphragm, 
  when 
  directly 
  irritated 
  by 
  current, 
  

   contracts 
  very 
  faintly, 
  whilst 
  the 
  neighbouring 
  muscles 
  contract 
  vigo- 
  

   rously. 
  Peristaltic 
  action 
  goes 
  on. 
  Electrodes 
  applied 
  to 
  vagus 
  appear 
  to 
  

   accelerate 
  peristaltic 
  action 
  ; 
  applied 
  to 
  splanchnic, 
  they 
  diminish 
  it. 
  

  

  3.7. 
  Ventricles 
  of 
  heart 
  have 
  now 
  contracted 
  firmly. 
  

  

  3.15. 
  Blood 
  taken 
  from 
  heart 
  and 
  great 
  vessels 
  has 
  coagulated, 
  but 
  

   not 
  firmly. 
  The 
  clot 
  is 
  small, 
  and 
  the 
  serum 
  very 
  red. 
  

  

  3.15. 
  Electrodes 
  to 
  sciatic 
  ; 
  no 
  reaction. 
  Blood 
  examined 
  under 
  

   microscope 
  ; 
  no 
  aggregation 
  in 
  rouleaux, 
  no 
  crenation 
  of 
  corpuscles. 
  

   Blood 
  neutral 
  to 
  test-paper. 
  

  

  "VVe 
  have 
  in 
  former 
  papers 
  remarked 
  that 
  when 
  the 
  cobra-poison 
  was 
  

   injected 
  into 
  the 
  jugular 
  vein 
  directly 
  and 
  caused 
  almost 
  immediate 
  

   death, 
  that 
  the 
  fatal 
  result 
  was 
  due 
  to 
  cessation 
  of 
  the 
  heart's 
  action 
  by 
  

   arrest 
  in 
  systole, 
  and 
  such 
  was 
  partially 
  the 
  case 
  in 
  the 
  last 
  experiment 
  

   (VII.), 
  made 
  for 
  the 
  purpose 
  of 
  comparison 
  with 
  Crotalus; 
  but 
  in 
  

   experiment 
  VI. 
  death 
  was 
  not 
  so 
  caused, 
  for 
  the 
  heart 
  continued 
  to 
  

   contract 
  for 
  about 
  23 
  minutes 
  after 
  apparent 
  death, 
  which 
  was 
  probably 
  

   due 
  to 
  the 
  sudden 
  and 
  total 
  annihilation 
  of 
  the 
  functions 
  of 
  the 
  

   medulla 
  and 
  cord, 
  no 
  reaction 
  to 
  a 
  strong 
  current 
  occurring 
  when 
  the 
  

   electrodes 
  were 
  applied 
  immediately 
  after 
  apparent 
  death. 
  

  

  In 
  this 
  instance 
  of 
  Ootofots-poisoning 
  it 
  is 
  also 
  to 
  be 
  remarked 
  that 
  the 
  

   coagulability 
  of 
  the 
  blood 
  was 
  destroyed, 
  whilst 
  in 
  that 
  by 
  cobra-virus 
  it 
  

   was 
  only 
  partially 
  so. 
  

  

  It 
  appears 
  from 
  the 
  results 
  of 
  this 
  experiment 
  that 
  the 
  direct 
  inocu- 
  

   lation 
  of 
  large 
  doses 
  of 
  the 
  virus, 
  whether 
  viperine 
  or 
  colubrine, 
  into 
  the 
  

  

  