﻿1875.] 
  

  

  Action 
  of 
  the 
  Crotalus-poison, 
  

  

  271 
  

  

  place, 
  and 
  to 
  the 
  naked 
  eye 
  the 
  mesentery 
  became 
  discoloured 
  by 
  patches 
  

   of 
  ecchymosis 
  in 
  the 
  course 
  of 
  the 
  small 
  bloodvessels, 
  like 
  the 
  foliage 
  on 
  

   the 
  branches 
  of 
  a 
  tree. 
  

  

  There 
  could 
  be 
  no 
  doubt 
  that 
  the 
  local 
  action 
  of 
  the 
  poison 
  had 
  a 
  marked 
  

   effect 
  in 
  producing 
  extravasation 
  of 
  blood. 
  

  

  Experiment 
  XIII. 
  

   A 
  similar 
  experiment 
  was 
  repeated 
  on 
  another 
  part 
  of 
  the 
  mesentery 
  

   of 
  the 
  same 
  cat 
  with 
  cobra-poison, 
  exactly 
  as 
  the 
  Crotalus--poison 
  had 
  

   been 
  applied 
  in 
  the 
  previous 
  experiment. 
  This 
  was 
  carefully 
  watched, 
  

   but 
  no 
  extravasation 
  took 
  place 
  ; 
  there 
  was 
  a 
  marked 
  difference 
  in 
  the 
  

   result 
  of 
  the 
  application 
  of 
  the 
  two 
  poisons, 
  at 
  all 
  events 
  as 
  far 
  as 
  these 
  

   two 
  experiments 
  were 
  concerned. 
  

  

  Experiment 
  XIV. 
  

  

  August 
  12t7i, 
  1874. 
  — 
  A 
  cat 
  was 
  chloralized 
  at 
  2.30 
  p.m. 
  Mesentery 
  

   exposed 
  and 
  placed 
  under 
  microscope 
  on 
  warm 
  stage. 
  

  

  Crotalus--poison 
  applied 
  to 
  mesentery 
  ; 
  circulation 
  soon 
  diminished 
  in 
  

   some 
  vessels 
  but 
  continued 
  vigorously 
  in 
  others. 
  Isolated 
  extra 
  vasated 
  

   patches 
  soon 
  made 
  their 
  appearance 
  of 
  a 
  triangular 
  form, 
  others 
  followed 
  

   and 
  coalesced 
  with 
  these 
  until 
  a 
  network 
  was 
  formed 
  in 
  the 
  course 
  of 
  the 
  

   vessels 
  all 
  over 
  the 
  field. 
  The 
  extravasation 
  soon 
  became 
  general, 
  the 
  cir- 
  

   culation 
  still 
  continuing 
  slowly. 
  

  

  Experiment 
  XV. 
  

  

  A 
  fresh 
  portion 
  of 
  mesentery 
  of 
  same 
  cat 
  exposed. 
  Intestines 
  be- 
  

   coming 
  cold 
  and 
  circulation 
  now 
  very 
  languid. 
  

   Cobra-poison 
  applied. 
  

  

  No 
  apparent 
  effect 
  produced 
  ; 
  but 
  the 
  circulation 
  is 
  very 
  languid, 
  

   indeed 
  has 
  almost 
  ceased, 
  so 
  that 
  the 
  results 
  of 
  this 
  experiment 
  are 
  not 
  

   conclusive. 
  

  

  Experiment 
  XI 
  V. 
  

  

  August 
  14:th, 
  1874. 
  — 
  A 
  cat 
  was 
  chloralized, 
  part 
  of: 
  mesentery 
  with- 
  

   drawn, 
  and 
  placed 
  under 
  microscope 
  on 
  warm 
  stage. 
  

  

  Dried 
  cobra-poison 
  dissolved 
  in 
  a 
  salt 
  solution, 
  '75 
  per 
  cent., 
  applied 
  to 
  

   the 
  mesentery 
  at 
  4.10 
  p.m. 
  

  

  4.14. 
  Circulation 
  is 
  languid, 
  almost 
  ceased 
  in 
  some 
  vessels. 
  

  

  4.18. 
  Slight 
  extravasation 
  taking 
  place 
  where 
  the 
  poison 
  has 
  been 
  in 
  

   contact. 
  

  

  4.20. 
  Extravasation 
  rather 
  more 
  obvious. 
  

  

  4.35. 
  Exposed 
  another 
  part 
  of 
  the 
  mesentery 
  ; 
  examined 
  the 
  state 
  of 
  

   the 
  circulation 
  before 
  applying 
  the 
  poison. 
  Blood 
  flowing 
  languidly. 
  

  

  Poison 
  applied 
  at 
  4.37 
  ; 
  at 
  first 
  it 
  seemed 
  rather 
  to 
  accelerate 
  the 
  

   movement 
  of 
  the 
  blood. 
  

  

  