﻿1875.] 
  

  

  Action 
  of 
  the 
  Crotalus 
  -poison, 
  fye. 
  

  

  275 
  

  

  1.45. 
  The 
  muscle 
  has 
  lost 
  its 
  irritability; 
  does 
  not 
  respond 
  to 
  the 
  

   strongest 
  current. 
  

  

  Experiment 
  XXVI. 
  

  

  At 
  the 
  same 
  time 
  (1.25 
  p.m.) 
  the 
  gastrocnemius 
  from 
  the 
  other 
  leg 
  or 
  

   the 
  same 
  frog 
  immersed 
  in 
  water. 
  Did 
  not 
  immediately 
  contract 
  like 
  

   that 
  placed 
  in 
  the 
  poisoned 
  solution. 
  

  

  1.30. 
  Contracts 
  strongly 
  to 
  current 
  at 
  15 
  c. 
  m. 
  of 
  Du 
  Bois 
  Eeymond's 
  

   coil, 
  more 
  than 
  the 
  poisoned 
  muscle 
  at 
  11, 
  at 
  the 
  same 
  moment. 
  

  

  1.45. 
  Contracts 
  distinctly 
  at 
  11, 
  whilst 
  the 
  poisoned 
  muscle 
  has 
  lost 
  

   all 
  irritability. 
  

  

  Prom 
  this 
  it 
  is 
  evident 
  that 
  the 
  poison 
  first 
  stimulates 
  the 
  muscular 
  

   fibre 
  to 
  contract, 
  but 
  rapidly 
  afterwards 
  destroys 
  its 
  irritability. 
  

  

  Experiment 
  XXVII. 
  

  

  The 
  gastrocnemii 
  of 
  a 
  frog 
  were 
  again 
  treated 
  in 
  the 
  same 
  way 
  as 
  in 
  

   the 
  previous 
  experiment, 
  with 
  precisely 
  the 
  same 
  results. 
  

  

  June 
  28t7i. 
  — 
  Made 
  several 
  experiments 
  with 
  cobra-poison 
  on 
  ciliated 
  

   epithelium 
  of 
  frog's 
  mouth, 
  and 
  found 
  that 
  it 
  at 
  first 
  accelerated, 
  then 
  

   destroyed, 
  the 
  action 
  of 
  the 
  cilia. 
  

  

  Experiment 
  XXVIII. 
  

  

  To 
  test 
  the 
  effects 
  of 
  Cobra-poison, 
  ivhen 
  swallowed, 
  on 
  the 
  Frog. 
  

  

  June 
  24:t7i, 
  1874. 
  — 
  At 
  2.25 
  p.m. 
  about 
  ^ 
  of 
  a 
  gr. 
  of 
  dried 
  cobra-poison 
  

   was 
  passed 
  down 
  a 
  frog's 
  throat. 
  

  

  ' 
  2.30. 
  Frog 
  making 
  violent 
  efforts 
  to 
  vomit. 
  Gaping. 
  Head 
  thrown 
  

   back 
  tetanically. 
  

  

  2.34. 
  Bloody 
  mucus 
  vomited 
  with 
  violent 
  efforts 
  *. 
  

  

  2.50. 
  Moves 
  with 
  difficulty 
  ; 
  is 
  becoming 
  paralyzed. 
  Efforts 
  to 
  vomit 
  

   continue. 
  

  

  3. 
  Much 
  the 
  same. 
  

  

  3.5. 
  Very 
  weak 
  ; 
  still 
  tries 
  to 
  vomit. 
  

  

  3.10. 
  Beflex 
  action 
  still 
  well-marked. 
  

  

  3.15. 
  Motor 
  nerves 
  apparently 
  quite 
  paralyzed. 
  

  

  3.20. 
  Apparent 
  death. 
  

  

  Artificial 
  Respiration 
  with 
  pure 
  Oxygen. 
  

  

  As 
  life 
  had 
  been 
  prolonged 
  for 
  many 
  hours 
  in 
  snake-poisoning 
  by 
  arti- 
  

   ficial 
  respiration 
  with 
  atmospheric 
  air, 
  it 
  was 
  thought 
  expedient 
  to 
  as- 
  

   certain 
  if 
  the 
  more 
  complete 
  ox} 
  r 
  genation 
  by 
  the 
  undiluted 
  gas 
  would 
  be 
  

   more 
  efficacious, 
  as 
  it 
  seemed 
  might 
  be 
  possible 
  ; 
  accordingly 
  the 
  following 
  

   experiment 
  was 
  made 
  on 
  the 
  24th 
  April, 
  1874. 
  

  

  * 
  This 
  experiment 
  is 
  especially 
  interesting, 
  as 
  showing 
  that 
  frogs 
  do 
  occasionally 
  

   vomit, 
  a 
  fact 
  which 
  has 
  been 
  denied 
  by 
  some 
  physiologists. 
  

  

  