﻿1875.] 
  

  

  Inflamjnation 
  of 
  Connective 
  Tissue. 
  

  

  311 
  

  

  up 
  in 
  blood-serum, 
  the 
  latter 
  method 
  being 
  found 
  more 
  certain 
  to 
  give 
  

   available 
  preparations. 
  

  

  The 
  only 
  appearance 
  observed, 
  anterior 
  to 
  a 
  complete 
  destruction 
  of 
  

   the 
  cell, 
  was 
  a 
  division 
  of 
  the 
  nucleus 
  into 
  two 
  or 
  more 
  parts. 
  In 
  

   serum 
  preparations 
  the 
  products 
  of 
  the 
  division 
  assumed 
  the 
  form 
  of 
  

   circles 
  of 
  highly 
  refractive 
  particles. 
  Similar 
  particles 
  were 
  sparsely 
  

   scattered 
  in 
  the 
  substance 
  of 
  the 
  cell. 
  

  

  The 
  area 
  of 
  any 
  one 
  circular 
  product 
  of 
  this 
  division 
  was 
  always 
  much 
  

   smaller 
  than 
  that 
  of 
  the 
  undivided 
  nucleus. 
  

  

  In 
  regard 
  to 
  the 
  stellate 
  cells, 
  the 
  author 
  questions 
  the 
  correctness 
  of 
  

   the 
  accepted 
  theory, 
  which 
  implies 
  an 
  identity 
  of 
  the 
  cell 
  and 
  its 
  pro- 
  

   cesses 
  with 
  the 
  visible 
  protoplasm. 
  He 
  considers 
  that 
  the 
  refractive 
  

   particles, 
  which 
  constitute 
  what 
  is 
  visible 
  in 
  the 
  cellular 
  protoplasm, 
  are 
  

   suspended 
  in 
  a 
  fluid, 
  similarly 
  to 
  the 
  pigment-granules 
  in 
  the 
  pigment- 
  

   cells 
  as 
  described 
  by 
  Mr. 
  Lister. 
  The 
  phenomenon 
  described 
  by 
  German 
  

   investigators 
  as 
  " 
  Zusammenballen 
  " 
  of 
  the 
  cell-processes, 
  he 
  attributes 
  

   to 
  a 
  collection 
  of 
  the 
  protoplasmic 
  particles 
  in 
  the 
  centre 
  of 
  the 
  cell, 
  

   similar 
  to 
  that 
  which 
  takes 
  place 
  in 
  concentration 
  of 
  pigment. 
  This 
  

   opinion 
  is 
  borne 
  out 
  by 
  a 
  comparison 
  of 
  gold 
  and 
  osmic-acid 
  prepara- 
  

   tions. 
  In 
  conditions 
  in 
  which, 
  by 
  the 
  former 
  process, 
  an 
  isolated 
  glo- 
  

   bular 
  body 
  is 
  seen, 
  osmic-acid 
  preparations 
  show 
  that 
  the 
  anastomosis 
  of 
  

   the 
  thread-like 
  processes 
  remains 
  complete. 
  Reasoning 
  analogically 
  from 
  

   the 
  results 
  obtained 
  by 
  gold 
  in 
  other 
  tissues, 
  he 
  infers 
  that 
  it 
  is 
  what 
  

   may 
  be 
  described 
  as 
  the 
  contents 
  of 
  the 
  cell 
  and 
  processes 
  which 
  stain 
  by 
  

   that 
  method. 
  

  

  Treatment 
  by 
  osmic 
  acid 
  is 
  the 
  only 
  reliable 
  method 
  by 
  which 
  he 
  has 
  

   obtained 
  satisfactory 
  preparations 
  showing 
  the 
  stellate 
  cells 
  in 
  the 
  in- 
  

   flamed 
  cornea. 
  The 
  advantages 
  of 
  this 
  mode 
  of 
  treatment 
  are 
  much 
  

   enhanced 
  by 
  subsequent 
  staining 
  with 
  red 
  aniline, 
  which 
  especially 
  differ- 
  

   entiates 
  the 
  protoplasm 
  and 
  processes. 
  Subsequent 
  staining 
  by 
  haBina- 
  

   toxylin 
  renders 
  the 
  nuclei 
  visible. 
  

  

  The 
  only 
  change, 
  except 
  that 
  of 
  destructive 
  disintegration, 
  observed 
  by 
  

   the 
  author 
  as 
  a 
  consequence 
  of 
  inflammation 
  in 
  the 
  stellate 
  cells 
  3 
  consists 
  

   in 
  the 
  anastomosing 
  processes 
  being, 
  in 
  gold 
  preparations, 
  occasionally 
  

   represented 
  by 
  fine 
  darkly 
  stained 
  lines, 
  on 
  which 
  are 
  a 
  series 
  of 
  small 
  

   globular 
  swellings 
  placed 
  at 
  short 
  regular 
  intervals, 
  giving 
  any 
  one 
  pro- 
  

   cess 
  an 
  appearance 
  identical 
  with 
  that 
  presented 
  by 
  an 
  ultimate 
  nerve- 
  

   fibrilla 
  in 
  a 
  gold 
  preparation. 
  The 
  same 
  appearance 
  is 
  also 
  to 
  be 
  seen 
  in 
  

   osmic-acid 
  preparations, 
  and 
  is 
  suggestive 
  of 
  points 
  of 
  communication 
  

   between 
  the 
  lumen 
  of 
  the 
  process 
  and 
  the 
  interfibrillary 
  space. 
  (This 
  is 
  

   the 
  only 
  form 
  in 
  which 
  the 
  author 
  has 
  seen 
  the 
  processes 
  of 
  the 
  stellate 
  

   cells 
  in 
  inflamed 
  cornese 
  in 
  gold 
  preparations. 
  They 
  are 
  usually 
  invisible 
  

   by 
  that 
  process.) 
  

  

  Appearances 
  indicative 
  of 
  a 
  dividing 
  nucleus 
  were 
  rarely 
  seen, 
  and 
  

   their 
  iuterpretation 
  is 
  doubtful. 
  Both 
  in 
  respect 
  to 
  the 
  nucleus 
  and 
  the 
  

  

  