﻿1875.] 
  

  

  Inflammation 
  of 
  Connective 
  Tissue. 
  

  

  313 
  

  

  certainty 
  in 
  osmic-acid 
  preparations. 
  They 
  are 
  found 
  in 
  groups 
  in 
  the 
  

   wider 
  spaces, 
  in 
  rows 
  in 
  the 
  nerve-channels 
  and 
  between 
  the 
  primary 
  

   bundles 
  (corneal 
  tubes 
  of 
  Bowman), 
  and 
  in 
  large 
  numbers 
  in 
  the 
  tracts 
  

   between 
  the 
  larger 
  bundles. 
  They 
  are 
  mostly 
  round, 
  sometimes 
  club- 
  

   shaped, 
  never 
  pointed 
  at 
  two 
  extremities 
  as 
  an 
  elongated 
  shuttle-shaped 
  

   mass 
  (that 
  is, 
  never 
  spinclelformig, 
  spiessartig). 
  A 
  small 
  minority 
  con- 
  

   sist 
  of 
  a 
  double 
  body 
  formed 
  by 
  two 
  rounded 
  globular 
  masses 
  joined 
  by 
  

   a 
  smooth 
  isthmus. 
  "When 
  stained 
  by 
  haematoxylin, 
  nuclei 
  are 
  found 
  in 
  

   either 
  end, 
  but 
  not 
  in 
  the 
  isthmus. 
  The 
  author 
  infers 
  that 
  we 
  have 
  here 
  

   a 
  corpuscle 
  in 
  process 
  of 
  division. 
  

  

  In 
  rabbit-corneae, 
  in 
  which 
  inflammation 
  has 
  lasted 
  about 
  a 
  week, 
  some 
  

   white 
  corpuscles 
  are 
  seen 
  with 
  uneven 
  contour 
  ; 
  and 
  bulging 
  outwards 
  

   from, 
  or 
  lying 
  close 
  beside, 
  them 
  are 
  bodies 
  evidently 
  nuclear, 
  and 
  which 
  

   are 
  affected 
  by 
  osmic 
  acid 
  and 
  subsequent 
  staining 
  with 
  red 
  aniline, 
  in 
  a 
  

   manner 
  identical 
  with 
  the 
  red 
  blood-corpuscles 
  seen 
  in 
  blood-vessels 
  in 
  

   the 
  same 
  preparation. 
  The 
  identity 
  of 
  the 
  escaped 
  nuclei 
  with 
  red 
  blood- 
  

   corpuscles 
  is 
  shown 
  by 
  a 
  comparison 
  of 
  their 
  respective 
  size, 
  evenness, 
  

   colour, 
  and 
  contour. 
  

  

  The 
  author 
  infers 
  a 
  production 
  of 
  red 
  blood-corpuscles 
  in 
  inflammation 
  

   from 
  the 
  nuclei 
  of 
  the 
  white 
  blood-cells. 
  

  

  In 
  observations 
  on 
  human 
  blood, 
  and 
  that 
  of 
  the 
  mouse, 
  by 
  staining 
  

   with 
  hematoxylin, 
  he 
  has 
  found 
  that 
  while 
  the 
  great 
  majority 
  of 
  the 
  red 
  

   corpuscles 
  do 
  not 
  quickly 
  stain 
  in 
  a 
  weak 
  solution, 
  there 
  are 
  some 
  which 
  

   at 
  once 
  stain 
  a 
  deep 
  blue, 
  and 
  that 
  there 
  are 
  white 
  corpuscles 
  in 
  which 
  

   a 
  narrow 
  protoplasmic 
  margin 
  encloses 
  a 
  deep 
  blue 
  nucleus 
  similar 
  in 
  con- 
  

   tour, 
  and 
  size 
  to 
  the 
  stained 
  red 
  corpuscles. 
  Amongst 
  the 
  red 
  corpuscles 
  

   of 
  the 
  frog 
  are 
  a 
  minority 
  which 
  are 
  recognized 
  as 
  being 
  red 
  corpuscles 
  

   by 
  their 
  size, 
  smooth 
  contour, 
  and 
  absence 
  of 
  granulation, 
  but 
  in 
  which 
  

   there 
  is 
  no 
  haemoglobin, 
  and 
  the 
  nucleus 
  quickly 
  stains 
  blue 
  in 
  solution 
  

   of 
  haematoxylin, 
  like 
  that 
  of 
  the 
  white 
  cells. 
  

  

  Transitions 
  occur 
  in 
  which 
  a 
  less 
  and 
  less 
  capacity 
  of 
  staining 
  on 
  the 
  

   part 
  of 
  the 
  nucleus 
  takes 
  place, 
  pari 
  passu 
  with 
  an 
  increase 
  in 
  the 
  colour 
  

   characteristic 
  of 
  haemoglobin 
  in 
  the 
  body 
  of 
  the 
  cell. 
  In 
  the 
  fully 
  deve- 
  

   loped 
  red 
  corpuscle, 
  the 
  nucleus 
  stains 
  only 
  after 
  it 
  has 
  been 
  for 
  some 
  time 
  

   in 
  contact 
  with 
  a 
  weak 
  solution 
  of 
  haematoxylin. 
  

  

  The 
  author 
  has 
  observed 
  in 
  the 
  blood 
  of 
  the 
  mouse 
  foetus 
  the 
  nuclei 
  

   of 
  the 
  nucleated 
  red 
  blood-cell 
  escape 
  from 
  the 
  larger 
  cell, 
  and 
  then 
  be- 
  

   come 
  indistinguishable 
  in 
  form 
  and 
  appearance 
  from 
  the 
  small 
  red 
  cor- 
  

   puscles 
  of 
  the 
  mature 
  animal 
  present 
  in 
  the 
  blood 
  under 
  examination. 
  

  

  These 
  observations, 
  taken 
  in 
  connexion 
  with 
  the 
  bodies 
  that 
  are 
  formed 
  

   in 
  the 
  spindle 
  cells 
  and 
  white 
  corpuscles 
  in 
  inflammation, 
  support, 
  as 
  the 
  

   author 
  believes, 
  the 
  doctrine 
  of 
  Wharton 
  Jones, 
  in 
  regard 
  to 
  the 
  forma- 
  

   tion 
  of 
  the 
  red 
  blood-corpuscles. 
  

  

  The 
  mode 
  of 
  formation 
  of 
  capillary 
  blood-vessels 
  he 
  believes 
  to 
  be 
  

   identical 
  in 
  inflamed 
  and 
  in 
  fcetal 
  tissue. 
  In 
  studying 
  this 
  subject 
  he 
  

  

  VOL. 
  XXIII. 
  2 
  B 
  

  

  