262 



Mr. A. W. Blyth. 



[Nov. 26, 



The table gives the results obtained at the ordinary temperature, 

 and also at the temperature of 35'5°. 



The effect of a temperature of 35*5° is remarkable, and goes far to 

 explain the happy effects of the so-called antiseptic or Listerian 

 method of surgery. The effect of the higher temperature is seen 

 mainly in the longer period of time between the infection and the 

 subsequent growth, e.g., when the phenol was present in the propor- 

 tion of 0*1 per cent., under these conditions the growth wasretarded to 

 the seventh and eighth day, and 0'25 of phenol which did not disinfect 

 with certainty at from 15 — 16° did so at 35'5°. 



Pyridine Series. — Pure samples of pyridine (C 5 H 5 N), picoline 

 (C 6 H 7 N), lutidine (C 7 H 9 N), collidine (C 8 H n N), parvoline (C 9 H 13 N), 

 and also acridine (C 13 H 9 N), and acridine hydrochlorate were placed 

 at my disposal by Mr. Benjamin Nickels. 



Solutions of the bases were made in 20 per cent, alcohol, and the 

 bacterium was experimented upon on the same lines as in the pre- 

 series of experiments. 



The table gives the general results obtained, and establishes well 



The Pyridine Bases. 



Days 



2. 



3. 



4. 



5. 



6. 



7. 



8. 



9. 



10. 



11. 



At 15 52— 























Pyridine 9 per cent 





T 



















1-6 „ 























2-0 „ 























Parvoline 0'45 .... 























083 „ 























115 „ 























025 „ 







+ 

















Picoline 0'9 „ 





+ 



















1-6 „ 





+ 



















2-3 







+ 

















30 























Lutidine 0*45 „ .... 







+ 

















083 , 











+ 













115 „ 











+ 













At 35 5°— 























Lutidine 0'5 „ .... 























At 15°-5— 























Collidine 0*45 „ .... 





+ 



















„ 0-83 „ 











+ 













At 35 5°— 























Collidine TO 























At 15°- 5— 























Acridine 01 ,, .... 

 „ hydrochloride 0'01 p.c. 

 At 35-5°— 





+ 

























+ 



































Acridine hydrochloride 0"01 























p.c. 























