74 



Messrs. Parkes and Wollowicz on the 



[Recess, 



man was the subject of the experiments, and he was placed on precisely 

 the same diet as is recorded in the former paper. 



The experiments were continued for 30 days, the man having abstained 

 from any alcoholic beverage for 16 days previously. During the first 10 

 days, water only was taken at dinner, during the next 10 days red Bor- 

 deaux wine was substituted for the water; 10 fluid ounces (284 cub. 

 centims.) being given on the first 5 days, and 20 fluid ounces (563 cub. 

 centims.) on the last 5 days. The wine was taken at dinner time, at a 

 quarter past 1 o'clock. In the last 10 days water was again given. 



The wine was a good claret, as it was thought best to use a superior 

 wine ; it was Haut Brion wine of second growth, of the vintage of 1863, 

 and was sold in London at the price of 60a*. per dozen. It contained 1 1 

 per cent, of alcohol. The free acidity was equal to about 3 grains per 

 ounce of tartaric acid (C 4 H 6 6 ); the total solids amounted to 21*76 

 grammes, and the fire-proof salts to 2*359 grammes per litre. Of this 

 amount of salts 2*027 grammes were soluble, and *332 insoluble. In the 

 former, phosphoric acid and chlorine were present in the amounts of *145 

 and '106 gramme per litre respectively; the insoluble salts contained 

 only '01/5 gramme of phosphoric acid per litre. In the 10 ounces of wine 

 there were therefore only 0*7 grain of phosphoric acid, and 0*46 grain of 

 chlorine. 



The ash was intensely alkaline, and, when neutralized with standard 

 acid, the alkalinity was found to be equal to 1*679 gramme of tartaric acid 

 (C 4 H 6 6 ) per litre. 



Only two circumstances (except the taking of wine) were different in 

 this set of experiments as compared with the former. 



The first experiments were made in February and March 1870, when 

 the weather was very cold ; the present were made in May and June 

 in very hot and dry weather. The only influence we could trace to this 

 altered condition of climate was that the amount of water allowed was in- 

 sufficient, and the man suffered some discomfort from thirst. We could 

 not perceive that any effect was produced on the nitrogenous elimina- 

 tion ; certainly there was no diminution. 



The other alteration was that the man had gained 4 lbs. in weight, and 

 was still gaining a little when the experiments were commenced ; he con- 

 tinued to do so slowly until the 24th day, when his health began to give 

 way and he lost weight. 



The experiments included the number of the pulse (taken in the recum- 

 bent position) every 2 hours from 8 a.m. to 10 p.m., tracings of the pulse 

 and respirations, the temperature of the axilla every 2 hours from 6 a.m. 

 to 10 p.m., the temperature of the rectum four times a day (the observa- 

 tions being taken with the same thermometers as on the former occasion), 

 the amounts of nitrogen, phosphoric acid, chlorine and free acidity of the 

 urine, and the weight, and in the two cases the amount of nitrogen in 

 the stools. 



