222 



Dr. J. T. Cash. 



traction is easily estimated. It is then found that the intestine from 

 a condition of entire rest or very faint contraction frequently passes 

 with great rapidity to a state of powerful and regular propulsive con- 

 traction. 



If the movement be registered by a stationary sound connected with 

 a manometer, the course of the contractions occurring at the part of 

 the fistulous intestine surrounding the bladder is recorded. It will be 

 observed then that the individual contractions develop gradually to a 

 maximum, and thereafter decline rapidly, their rhythm or rate of 

 recurrence being very constant throughout. 



Experiment V, Curve IV. — Administration of Meat to Fasting 

 Animal during Absence of Contraction of Intestine (fixed sound 

 and mercurial manometer) . 



Experiment V (Curve IV). — Dog fasting, sound, moderately dis- 

 tended with water, introduced 3 cm. into upper fistulous opening. 

 The contraction round the sound as a result of its introduction 

 and extension occurred regularly at the rate of ten for V, After 

 spontaneous movement had ceased the smell of the meat produced 

 excitement with distinct contractions, which did not entirely disappear 

 for 3' 30". 



0' 0". When rest had again intervened, a small piece of meat 



weighing 5 grams was given. 

 1' 30". Another piece of the same size. Both of these were 



swallowed the instant they were presented. 

 1' 45". Contraction commenced at the rate of seven in 40". 

 3' 20". Active contractions reached their maximum. Some tonic 



contraction is still seen between active compression of the 



sound, so that the curve remains elevated above the abscissa. 

 4' 16". The active contractions which had been declining markedly 



for 30" came to an end,' and were succeeded by a series of short 



waves which lasted for V till at 

 5' 16". The intestine came to rest. 



Five minutes later a piece of meat was again offered, faint move- 

 ment being present at the time, the maximum of the powerful con- 

 tractions was reached in 40", in exact correspondence with the 

 former experiment. In the first result there were nineteen well- 



