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merit in which another horse (No. 3) recei ved no less than 2180 c.c. 

 serum toxine in the space of a fortnight without any apparent injury. 

 The serum of this animal was tested during the first and second 

 weeks, before it had received any broth toxine, and it was found that 

 l/300thand 1 /500th of a c.c. respectively protected guinea-pigs against 

 ten lethal doses. On the third week l/850th of a c.c. protected, and 

 at the end of a month l/1250th of a c.c. sufficed. [The large amount 

 of antitoxine produced during the first two weeks, when the horse 

 received serum toxine alone, was quite unexpected, and leaves still 



