No. 563] EFFECT OF INTOXICATING MALE PARENT 655 



different ways; certain ones become drowsy and stupid, 

 while others become excited and sometimes vicious during 

 the treatment, constantly fighting and biting at others 

 in the tank. One male always had to be treated alone on 

 this account. The fumes are inhaled into the lungs and 

 pass directly into the circulation, so that the animals show 

 signs of intoxication very soon after being put into the 

 tank, yet the intake of alcohol is so gradual that they 

 may remain for one hour or more without becoming 

 totally anesthetized. The mucosa of the respiratory tract 

 is considerably irritated during the first few days or 

 weeks of the treatment, but later becomes hardened and 

 little effect can be noticed. The cornea of the eye is 

 greatly irritated and often becomes milky white and 

 opaque during the first few months; but later this clears 

 up in most of the specimens and the animal is able to see 

 perfectly, though one male that has been treated for 32 

 months is now entirely blind. The general condition of 

 the animals under the treatment is very good; they all 

 continue to grow if treated before reaching their full 

 size, and become fat and vigorous, taking plenty of food 

 and behaving in a normal manner in every particular. 



Certain of the animals have been killed at different 

 times during the experiment and their organs and tissues 

 studied microscopically; all have seemed entirely normal. 

 The tissues of one female were examined after she had 

 been treated for over a year, and the heart, stomach, 

 lungs, liver, kidney, etc., were all normal. She was gen- 

 erally fat but there was no fatty accumulation in the 

 parenchyma of any of the organs except possibly a slight 

 excess in the adrenal glands. 



As mentioned above several of the animals, both males 

 and females, have been partially castrated during the 

 experiments and the ovaries and testis have been found 

 to be in healthy condition. 



The treated animals are, therefore, little changed or 

 injured so far as their behavior and structure goes. 

 Nevertheless, the effects of the treatment are most 



