No. 563] EFFECT OF INTOXICATING MALE PARENT 657 



In all 124 matings of treated individuals have been 

 made. One hundred and three of these have reached 

 full-term and are recorded. Twenty-one matings are not 

 yet due. From the 103 full-term matings only 52 young 

 have survived and most of these are somewhat under 

 size and show their affected condition in the type of off- 

 spring to which they give rise. Yet their parents were 

 all unusually large and originally strong animals. 



From 35 control matings 56 healthy offspring have 

 been derived which continue to produce normal animals 

 in the following generations, in a few cases now to the 

 fourth generation. 



A tabulated summary of the results may be arranged 

 as indicated in Table 1. The conditions of the animals in 

 the mating pairs are shown in the first column of the 

 table and the total results of the matings are indicated 

 in the following columns. 



The first horizontal line gives the record when alcoholic 

 males are paired with normal females. Fifty-nine such 

 matings have reached term, 25 of these gave negative 

 results or early abortions. Some embryos were aborted 

 during very early stages and were generally in such poor 

 condition when found in the cages that little could be 

 learned from them. They were partially or completely 

 eaten by the mother in most cases. The males were 

 always kept with the females during favorable periods 

 for a number of days, usually about three weeks, and 

 conception should have occurred in all cases, as it did 

 with the control matings. 



Thirty-four of the 59 matings resulted in conceptions 

 which ran the full term. Eight, or about 24 per cent, of 

 these, were stillborn litters, consisting in all of 15 indi- 

 viduals. Most of these were somewhat premature; in a 

 few cases their eyelids were still closed and the hair was 

 sparse on their bodies. (A normal guinea-pig at birth is 

 well covered with a hairy coat, its eyelids are open and it 

 very quickly begins to run about. ) 



Twenty-six, or only 44 per cent., of the matings pro- 



