428 Messrs. J. N. Langley and W. Lee Dickinson. [Nov. 21, 



tines is not abolished, but that upon the movements of the stomach in 

 the main at any rate is abolished. Our experiments are not sufficiently 

 numerous, especially with regard to the connexion of the coeliac 

 ganglion with the stomach, to make it certain that the one ganglion 

 is entirely connected with the fibres to the intestine, and the other 

 the fibres to the stomach, but we think they show that in the main, and 

 possibly altogether, the stomachic inhibitory fibres of the splanchnic nerve 

 end in the cells of the coeliac ganglion, and the intestinal inhibitory fibres 

 of the splanchnic end in the cells of the superior mesenteric ganglion. 

 The vagus is said to send fibres to the ganglia of the solar plexus. 

 "We find, however, that copious application of nicotin to the plexus on 

 both right and left sides of the body does not interfere with the move- 

 ments of the stomach and intestines produced by stimulating the 

 vagus in the neck : that is to say, the motor fibres of the vagus do not 

 end in the nerve cells of the solar plexus. 



We may note that after nicotin has been applied to the ganglia of 

 the solar plexus the spontaneous movements of the intestine become 

 more pronounced ; that the ganglia recover in twenty to thirty minutes 

 from their state of paralysis ; and that to produce paralysis a second 

 time a larger amount of nicotin is required. 



The connexion of the vaso-motor fibres of the splanchnic with the 

 nerve cells of the solar plexus can be determined by taking a tracing 

 of the arterial blood pressure and stimulating the splanchnic before 

 and after the application of nicotin to the ganglia. In the rabbit and 

 cat, brushing either the coeliac or the superior mesenteric ganglion 

 with 1 per cent, nicotin sulphate diminishes the effect of stimulating 

 the splanchnic. The rise of blood pressure produced is much less 

 than previous to the application of nicotin. By applying nicotin to 

 both ganglia, being careful not to allow any to reach the renal plexus, 

 the rise of blood pressure caused by stimulating the splanchnic is 

 reduced to very small limits — in the rabbit, indeed, there may be no 

 rise of blood pressure — and, by applying it to the renal plexus as 

 well, the effect of splanchnic stimulation on the blood pressure is 

 abolished. 



We have obtained some evidence that, as in the case of the inhibitory 

 splanchnic fibres, so the vaso-motor splanchnic fibres for the area 

 of distribution of the coeliac artery run to the coeliac ganglion, and 

 those for the area of distribution of the superior mesenteric artery 

 run to the superior mesenteric ganglion ; but the method of deter- 

 mining this, viz., by observing the state of pallor of the viscera, often 

 gives unsatisfactory results. 



Bradford has recently shown that vaso-dilator fibres run in the 

 splanchnics to the kidney, and probably to the stomach and small 

 intestines. We find that after nicotin has been applied to the ganglia 

 of the solar and renal plexuses stimulation of the splanchnics causes 



