•266 



Dr. W. M. Haffkine. 



between the date of inoculation and the occurrence of a death from 

 plague in the families. The first row of figures refers to occurrences in 

 uninoculated members, the second to occurrences in inoculated, while 

 the small figures show the number of deaths which occurred in each 

 group on those days : — 



Deaths from plague occurred in uninoculated — 



32 41 53 72 83—103 113 12 i 151 i6i 19 1 20 1 21 1 24 1 32 1 and 42 1 , 



and in inoculated 



— 9 1 I2 1 andl4 1 



days after date of inoculation. 

 There had elapsed therefore eight days, during which eleven deaths 

 from plague occurred among the uninoculated members of the families, 

 before the first death took place in an inoculated case. The inocula- 

 tion has again acted, so to say, immediately ; or, to use the mode of 

 expression which we have adopted, has exercised its protective effect 

 within the time necessary for the subsidence of the general reactionary 

 symptoms produced by the inoculation. 



The investigation in this village was carried out by Surgeon-General 

 Harvey, the Director-General of the Indian Medical Service, and a 

 committee of British and native officials. Every member of the famih^ 

 who survived was seen, his particulars verified from the documents, 

 and every detail was confirmed from the registers kept at the time,, 

 and from the testimony of the whole of the villagers, who were present 

 throughout the inquiry. 



Experiments op a Large Scale, Average of the Results obtained, 



I have dwelt so long upon the description of the above experiments 

 not because they were the largest in volume or the most striking 

 which were made, but because they were the most precise of all, and, 

 so far as I am aware, free from any possible loophole of mistake. 



I made prolonged and detailed observations in very severely affected 

 communities of Lanowlie, in a population of 700 people, and among the 

 followers of the artillery at Kirkee, numbering at the time 1530. Very 

 complete data were collected by Professor Eobert Koch and Professor 

 Gaffky, of the German Government Plague Commission, by Major 

 Lyons, I. M.S., of the Bombay Medical Establishment, and by myself, 

 in the Portuguese colony of Damaon, in a population of 8230 indivi- 

 duals, during a frightful outbreak of plague there, which lasted more 

 than four months, in 1897. A minute investigation extending over 

 four months, was made by me in the Khoja Mussulman community of 

 Bombay, numbering some 12,000 people, where about half of the total 

 number were inoculated under the auspices of His Highness the Aga 

 Khan. A most comprehensive inoculation campaign, and with widely 



