256 



Dr. V. Harley. On the Breaking-up 



passed through, the pylorus during this time. Of the total fat only 

 0*080 gram was found as neutral fat, so that its percentage pro- 

 portion amounted to only 12*84 per cent., no less than 61 '83 per 

 cent, of the neutral fat Laving been broken up since it traversed 

 the pylorus. 



The free fat acids increased to 0*522 gram, therefore the percen- 

 tage of the total fat present as fat acids was 83*46. As originally 

 only 3' 78 per cent, of the total fat was in the form of free fat acids, 

 therefore 79*68 per cent, of the neutral fat has been broken up into 

 free fat acids in its passage along the stomach and small intestine, 

 and as the stomach contained 24*81 per cent., therefore 55*87 per 

 cent, of the free fat acids had been formed in the small intestine. 



The quantity of fat acids present as soap in the small intestine 

 was only 0*021 gram, but the total quantity of fat being so small the 

 percentage was 3*70. 



It would thus appear as if 2*37 per cent, of the ether extract 

 had been converted into soap in its passage from the mouth to the 

 caecum, and since 0*19 per cent, was found in the stomach, 2*18 per 

 cent, had been formed in the small intestine. 



The large intestine contained 0*741 gram of total fat, of which 

 0*229 gram remained in the form of neutral fat, and the percentage 

 of the neutral fat was 30*91, i.e., somewhat higher than that found 

 in the small intestine, although less than half the percentage in the 

 stomach. The free fat acids left in the large intestine were 0*452 gram, 

 i.e., 61*03 per cent, of the total ether extract present, the quantity is 

 therefore less than is present in the small intestine, but higher than 

 that in the stomach. 



The fat acids combined as soap in the large intestine were 

 0*059 gram, so that the percentage was 8*06 of the total fat. 



With regard to the absorption of fat, in this case we see that 

 where 12*027 grams were given only 9*479 were regained after seven 

 hours' digestion, so that at least 2*548 grams had been absorbed, i.e., 

 21 per cent, of the total given during the seven hours' digestion. 

 However, as no fat is probably absorbed from the stomach, we ought 

 only to calculate the percentage absorption from the 3*911 grams 

 which had passed into the small intestine, i.e., 65*16 per cent, of this 

 had been absorbed. 



The Splitting up of Fat in various parts of the Alimentary Canal in 

 Dogs on a Milk Diet and in which the Pancreas had been removed. 



Having shown the manner in which fat is broken down in the 

 intestines of dogs under normal circumstances, we can now consider 

 the changes that occur in the fats when milk is given to dogs in 

 which the pancreas has been previously removed. 



