of Fat in the Alimentary Canal. 



257 



In the following experiments, as has been already said, the 

 pancreas was removed on the second day of fasting, and the animals 

 allowed to fast still further two days after the operation, the rectuni 

 being washed out with copious warm water enemas, as by this means 

 it was hoped to rid the intestines of any residue of pancreatic 

 secretion which might otherwise be present, and at the same time 

 that the washing out would diminish the bacteria of the large 

 intestine to a considerable extent. 



In the four following dogs in no case was there, by analysis, any 

 evident absorption of fat from the intestines during the space of four 

 to seven hours. At the same time, the fact that the quantity of fat 

 found equalled or surpassed the quantity of fat given at the end of 

 this time, is no definite proof that no absorption of fat took place 

 from the large intestine. In all probability there was some absorp- 

 tion, as the lymphatics shone out as white lines and had not the 

 appearance of those normally present in fasting animals, though 

 they were not so prominent or filled as was the case in normal dogs 

 during the same period of digestion. The remarkable fact that the 

 quantity of fat was equal to, or in excess of, that given will appear to 

 be explained by the character of the intestinal excretion, or so-called 

 secretion, which has now been practically demonstrated to be always 

 present by Hermann, Ehrenthal, Berenstein, and Fr. Voit, which, is 

 in all probability a substance rich in fat and very much more profuse 

 than we are ordinarily led to believe. 



Table IV.— Weight, 6*19 kilos. Total Extirpation of Pancreas. Dog 

 being given Milk forty-eight hours after Removal of Gland and 

 killed by Chloroform four hours after the Diet. 





Total ether 

 extract. 



Neutral fat. 



Free fat 

 acid. 



Fat acids as 

 soap. 



Total. 



p. c. 



Total. 



p. e. 



Total. 



p. c. 



Total. 



p. c. 



7-602 



7-406 

 1 -456 

 0-444 



100 



100 

 100 

 100 



7*350 



4-5i3 

 0-820 

 0-159 



96-68 



60-94 

 31-17 

 35 81 



0-248 



2-727 

 0-452 

 0-271 



3-26 



36-82 

 56 -55 

 61 -04 



0-004 



0-166 

 0-184 

 0-014 



0-06 



2-24 

 12-48 

 3 15 



Found in — 



Small intestine. 

 Large intestine. 



In Table IV the total quantity of fat given was 7'G02 grams, and 

 alter the period of luur Lours, i.o kss than 7"4.06 grams still 

 remained in the stomach, so that during four hours only 0196 gram 

 had entered the intestines, or but 2'58 per cent, of the quantity 



