262 



Dr. V. Harley. On the Breaking-up 



reason, there was, towards the end of the seven hours' digestion 

 diarrhoea which necessitated the collecting of some of the faeces 

 passed, and by reason of this there was a possibility of some slight loss. 



This case alone, of all the dogs in which the pancreas was 

 removed, indicated any absorption of fat, for ont of the 12*027 grams 

 of the fat given 0*533 gram was not recovered. It was, however, 

 perfectly obvious that in this experiment this deficit was attributable 

 to loss in collection of the faeces, although everything to hinder 

 such an error was attempted. 



The stomach contained 9*358 grams of fat, of this no less than 

 9*177 grams was in the form of neutral fat, In fact, 98*07 per cent, 

 of the total fat was present in this case as neutral fat, while the 

 milk given contained only 95*90 per cent. 



The free fat acids in the milk given contained 0*455 gram, 

 while in the stomach only 0*159 gram was found; that is to say, 

 1*70 per cent, of the total fat only was present as fat acids in the 

 stomach. Soaps also were 0*022 gram, and the percentage 0*023. 



In this dog alone, of either the normal dogs or those in which the 

 pancreas was removed, was there no indication of breaking up of 

 neutral fat into free fat acids in the stomach, as far as the total 

 quantity of fat acids found in the stomach was concerned. The 

 explanation of this is very difficult. It may be due to the fact that 

 the milk fat in this case had very considerably broken up before it 

 was administered, the milk being somewhat acid, and it had been 

 boiled down considerably in order to decrease the volume given. 

 The quantity of fat which had left the stomach during the seven 

 hours' digestion was no less than 22*19 per cent, of the total given, 

 that is, much more than occurred in any of the other dogs in which 

 the pancreas had been previously removed. In fact, this out-flow is 

 more like the normal dogs. It is, therefore, possible that the soaps 

 and fat acids which, had been formed in the stomach had to a con- 

 siderable extent left it, and if to a greater extent than the neutral 

 fat had thus caused the percentage of neutral fat to be higher than 

 that given. 



The quantity of fat in the large gut was more than in the small 

 intestine, and this also was exceptional, as in all the other cases the 

 reverse was found after seven hours, and it can be only explained by 

 the fact that on account of the milk being sour and the diarrhoea 

 which occurred, there was a hurrying along of the contents of the 

 alimentary canal. 



The quantity of fat in the small intestine was only 0*464 gram, of 

 which 0*075 gram was present as neutral fat ; that is to say, only 

 16*17 per cent, of the total fat was present in the stomach as neutral 

 fat. The fat acids on the other hand were no less than 0'361 gram, 

 that is 77*79 per cent, of the total fat present in the small intestine. 



