386 Mr. J. N. Langley and Mr. W. L. Dickinson. [Mar. 27, 



3.59. Stim. sy., 30 sees. ; good constriction of artery of ear ; slight pallor of 



mouth and of conjunctiva, no effect on eyelid or nictitating membrane. 

 . 4.0. Stim. sy., 60 sees. ; complete pallor of ear, slight pallor of conjunctiva, no 



dilation observed in pupil, but it is now a little larger than at 3.57. 

 4.5. Stim. sy., 10 sees. ; fair pallor of conjunctiva, moderate dilation of pupil. 

 4.7. Stim. sy., 10 sees. ; eyelids open slightly (previous to the stimulation the 



eyelids were pressed together). 

 4.13. Stim. sy., 30 sees. ; pallor in lips and mouth is bilateral, but chiefly on the 



stimulated side. 



4.19. Stim. sy., 30 sees., c = 6 ; eye opens and pupil dilates well, no movement 

 of nictitating membrane. 



The Gat. — In the cat, the secretory nerve cells of the superior 

 cervical ganglion are paralysed before any others. After a small 

 dose of nicotin (3 to 5 mgm.), stimulation of the cervical sympathetic 

 causes, for a short time, no secretion of saliva, but still causes, or may 

 cause, all the other effects normally seen as the result of the stimula- 

 tion. The difference in the ease and duration of paralysis is in this 

 case very striking. On the other hand, there is often very little 

 difference in the ease of paralysis of the nerve cells of the superior 

 cervical ganglion, which are connected with other classes of nerve 

 fibres. There are some differences which are constant, but which 

 vary very considerably in degree. In the following experiment, the 

 difference between the time of paralysis of the vaso-motor effects on 

 the ear and the dilator effect on the, pupil is the maximum we have 

 found. 



Experiment V. 



Cat (C. p. 24). Chloroform given, then morphia subcutaneously, and occasionally 

 chloroform and ether. Cannula in the duct of the left sub-maxillary gland. Sym- 

 pathetic in neck tied and cut on left side. Cut left chordo-lingual. The pupil is 

 rather large; stimulation of the sympathetic with a weakish current (<? = 9) causes 

 the nictitating membrane to be drawn back, the eye to open, the pupil to dilate, the 

 artery of the ear to constrict, and a secretion of saliva. 



12.53. Inject into crural vein, 5 mgm. nicotin. The injection causes, amongst 

 other effects, those described above as resulting from stimulation of the 

 sympathetic. 



1.0. Stim. sy., c = 9. Moderate opening of eye, dilation of pupil, and constric- 

 tion artery of ear ; no secretion. 

 1.5. Stim. sy., c = 9 ; effects as before. 

 1.13. Stim. sy., e = 9 ; secretion also. 

 1.18. Inject 5 mgm. nicotin. 

 1.28. Stim. sy., c = 9 ; no effect. 



1.45. Stim. sy., c = 9; slight constriction artery of ear, no effect on pupil or 

 on secretion. 



1.50. Stim. sy., c — 9 ; constriction artery of ear, and slight dilation of pupil. 

 1.53. Stim. sy., c = 9 ; as before, and eye opens a little. 

 2.5. Stim. sy., c ~ 9 ; as before, but still no secretion. 



The effect of the sympathetic upon the nictitating mem"! 



