1890.] Secretion of Bile in a Case of Biliary Fistula. 507 



Eighthly. — More bile is excreted during the day than at night, the 

 excess varying between 5 oz. and 3 dr. 



Ninthly. — The excretion of bile seems to go on constantly and with 

 great regularity. 



Tenthly. — The excretion is apparently not materially influenced by 

 diet. 



Eleventhly. — The pigment of fresh human bile is biliverdin. 

 Twelfthly. — The supposed cholagogues investigated seem to 

 rather diminish than increase the amount of bile excreted. 



Mr. Fairley's Analysis. 



Analysis of bile drawn from biliary fistula (Mrs. V. B.), collected 

 April 13th, 10 a.m. to 10 p.m., and April 13th— 14th, 10 p.m. to 

 10 a.m., 1889. 



Columns I, II, III refer to the whole bile and gall-bladder fluid : 

 Column I, first twelve hours ; Column II, second 12 hours ; and 

 Column III, the whole fluid collected during twenty-four hours. 

 Column IV gives the composition of the bile calculated without the 

 gall-bladder fluid. . 



I. 



12 hours' bile, 

 10 a.m. to 10 P.M. 

 April 13. 



Quantity 570 c.c. 



Specific gravity . . T0085 

 Reaction Alkaline. 



The bile contains in 1000 parts : — 



Water 982 10 98179 



Total solids 17 90 18" 21 



1000-00 1000-00 

 The solid matter of the bile contains : — 



Cholesterin 



Fatty matter (free) 



Fat combined 

 (chiefly sodium 

 stearate) 



Sodium glyco- 

 cholate 



Sulphur equal to 

 sodium tauro- 

 cholate 



Organic substances 

 precipitated by 

 alcohol, chiefly 

 VOL. XLVII. 



0-44 

 011 



0-90 

 7-45 



087 



II. 



12 hours' bile, 

 10 p.m. to 10 A.M. 

 April 13—14. 



370 c.c. 

 1-0090 



045 

 0-12 



108 

 7-60 



0-094 



III. 



24 hours' bile, 

 April 13—14. 



940 c.c. 

 10087 



981-98 

 1802 



1000-00 



0'45 

 0-12 



0-97 

 7'51 



0*09 



24 hours' bile, 

 corrected for 

 gall-bladder 

 fluid. 



868 c.c. 

 1-0086 



981-76 

 18-24 



100J-00 



0-45 

 012 



0-97 

 7'51 



009 



2 p 



