190 



Pharmacology of Indian Cobra Venom. [Jan. 18, 



stimulation may be so intense as to overcome the maximum inhibitory- 

 impulse, and then the heart dies in systole with a quickened beat, and 

 is found after death as hard as a contracted post-partum uterus. Under 

 such circumstances, any increase in the force of the heart is tem- 

 porary, for the beat is probably a very partial one, the heart passes 

 through a stage of excitement into one of increasing systolic tonus, in 

 which the contractions are very limited in extent. 



A cknowledgments. 



In conclusion, I desire to express my indebtedness to all who have 

 so ungrudgingly helped me in my work. I owe my thanks to one and 

 all of Sir Thomas Fraser's and Professor Schafer's assistants, but 

 especially to Drs. Sillar, Carmichael, and Hering, who were always 

 willing to aid me in any way in their power. Messrs. Burnett, Jolly, 

 and Locherby, who gave up much of their time to work regularly for 

 me as my volunteer assistants, did excellent work throughout, and I 

 most gratefully acknowledge that, but for their aid, the work could 

 not have been done in the time. 



The help given me by Sir Thomas Fraser and by Professor Schafer 

 I have already acknowledged. It is not possible for me to do justice 

 to it, or to the unvarying kindness I met with from them both. 



Lastly, but far from least, my acknowledgments are due to 

 the Secretary of State for India, to the Government of India, and 

 to the Government of Madras, for the opportunity that has been given 

 me to carry out this work. 



