Virulence of Desiccated Tubercular Sputum. 497 



" Plot B." 



Animal. 



No. 



Distinctive 

 marks. 



Killed or 

 died. 



Summary of post-mortem 

 results. 



Rabbit .... 



T 1 



Right fore- 

 paw red 



Died after 

 25 days. 

 23.6.1900 



Generalised tuberculosis. 

 Specially marked in respi- 

 ratory system. Lungs 

 crowded with tuberculous 

 areas, distributed equally 

 through the organ. 



Rabbit .... 



T 4 



Red nose . . . 



Killed. 

 4.10.1900 



Tuberculous. Abundant tu- 

 bercle in lung structure. 

 Glands of fauces much en- 

 larged and tuberculous. 

 Bacilli found in abundance. 



Rabbit .... 



T 5 



Blue nose . . 



Killed. 

 4.10.1900 



Tuberculous. Lungs crowded 

 with miliary tubercles. 

 Kidneys much enlarged, and 

 covered with tuberculous 

 nodules. Bacilli found in 

 abundance. 



Guinea-pig 



T 9 



Right fore- 

 paw red . . 



Killed. 

 4.10.1900 



Tuberculous. Disease not 

 marked, and confined wholly 

 to rare tubercles in lung 

 structure. Bacilli found, 

 but in small numbers. 



Guinea-pig 



T 10 



Both fore- 

 paws red 



Killed. 

 4.10.1900 



Non -tuberculous. Organs all 

 healthy. 



G-uinea-pig 



T 11 



Righ fore- 

 paw blue 



Killed. 

 4.10.1900 



Non-tuberculous. All organs 

 healthy with exception of 

 lungs. These much con- 

 gested and patchy, but no 

 perceptible tubercle. No 

 bacilli found. 



From the above it will be seen that, eliminating one guinea-pig 

 which died at an early stage of the experiment from other causes, 

 80 per cent, of the experimental animals were found at death to be 

 suffering from tuberculosis in a very marked degree, and although in 

 most cases this was generalised, yet in all it was the respiratory system 

 in which the disease was most marked. The state of many of these 

 was described by Sir George Brown (to whom I am very greatly 

 indebted for the kind and unfailing aid he has given me in checking 

 and supervising the results of every post-mortem) as extraordinary, and 

 the specimens preserved will show to what an extent these organs were 

 affected. 



Two animals alone remained unaffected, and these were found quite 

 free from tubercle when killed at the end of five months from the date 



2 N 2 



