468 



Mr. G. F. Dowdeswell. 



[Jan. 18, 



on the other hand, the doctrine of an increase of virulence in septic 

 fluids in successive generations has "been again affirmed by Professor 

 Rosenberger* in relation as appears to both the forms of disease 

 here in question, without, however, giving any detailed account of the 

 experiments on which he grounded his opinion. 



In conclusion I have to thank the British Medical Association, 

 through the Scientific Grants Committee, for assistance in defraying the 

 expenses of these experiments. 



Table I. — Showing the Result of the Subcutaneous Injection of Septic 

 and Septichsemic Blood in different quantities in Rabbits. 



No. 



1 



1 



2 



2 



3 



3 



4 





5 



» 



6 



» 



7 





8 



4 



9 



5 



10 



6 



11 



7 



12 



j> 



13 



j> 



14 



j> 



15 



1 



16 



2 



17 



}> 



18 





19 





20 





23 

 24 



S3 



<D -1-3 

 3 



11 



Matter injected. 



Putrid bullock's blood dil. 

 Blood of No. 1 diluted. . . 



Quantity. 



J> 



2 



j» 



jj 



2 



« 



5> 



2 



j> 



JJ 



2 



j j 



>J 



2 



>5 



» 



3 



J> 





8 





JJ 



9 



» 



JJ 



10 







10 



J) 





10 



J) 



JJ 



10 





Putrid bullock's blood dil.. . 

 Blood of No. 15 diluted. . . . 



jj jj 15 „ 



jj j j 15 „ 



jj jj 1^ jj . . . • 



jj jj 15 „ . . . . 



gtt. 

 3-0 

 1 



_i_ 



1 o 



Too 



To~o"b 

 i 



ioooo 

 ToooTTo 



3 

 3 

 3-0 

 i 



1 oo 

 TooTTo 



100 0(10 00 



5 



1000000 



Eesult. 



Died within 40 hours. 



„ 24 „ 

 Died in 25 hours. 

 „ 24 „ 

 „ 25 „ 

 Died within 40 hours. 



„ „ 27 „ 

 Died iD 23 hours. 

 Died within 48 hours. 



„ „ 20 „ 

 Died in 20 hours. 



" 2 ?i " 

 jj 2o^ 



„ 20 „ 



Died within 48 hours. 



„ 24 „ 



jj jj 35 



jj jj 3£> „ 



„ 48 „ 



Survived, abscess formed 



100 0000 

 1 000000 oo 



Infection continued through successive generations up to the 10th. 

 Blood of rabbit of 10th 



generation diluted 



10000000 



_L 



1O0COO0O0 



Died in 21 hours. 

 Died after 27 hours, 

 within 40 hours. 



Note. — The quantities employed are here given in drops (minims), in 

 order that they may be comparable with the experiments of others on 

 the same subject. 



* " Ctrlb. f. d. Med. Wiss.," 1882, No. 4, p. 66. 



