126 



Dr. W. Stirling and A. Rannie. 



Rindfleisch is inclined to believe that small portions of the " hae- 

 matin-containing contents must pass through pores in the cell 

 membrane, or through holes produced in some other way in the 

 same." Bat Preyer remarks* that such forms of coloured corpuscle 

 have no membrane. Bealef found similar forms with long thread-like 

 processes which became separated from the parent corpuscle when a 

 drop of blood was warmed. 



Sometimes another series of phenomena is obtained. Large glo- 

 bular or flask-shaped processes are given off from the margins of 

 the corpuscles. (Fig- 6, p, q.) It may be at one side or on both. 

 Some of them become detached, and coalesce to form globular or semi- 

 globular large masses, which float off into the surrounding fluid, and 

 are ultimately dissolved. Ultimately the nucleus undergoes the same 

 changes as have already been described. 



Sulpho-Cyanide of Potassium. 

 A 10 per cent, solution of this salt, gave exactly the same results 

 as the corresponding salt of ammonium. 



Ammonium Chromate. 



When a drop of frog's blood was mixed in the cold with a drop of a 

 5 per cent, solution of this salt, the corpuscles were first observed to 

 take on the barred appearance of the perinuclear part, described as part 

 of the effect of citric, tartaric, and other acids, &c. The nucleus was 

 more distinctly seen and was pale and slightly granular. Small coloured 

 droplets were soon observed to form at the margin or periphery 

 of the corpuscles. The corpuscles then usually became more or less 

 regularly crenated, and the small yellow coloured droplets began to 

 assume a beaded appearance on the surface or edges of the corpuscles. 

 They then began to exhibit active Brownian movements. The cor- 

 puscles had by this time again become homogeneous in appearance, 

 and appeared to be very mobile or plastic, as they changed their shape 

 with great facility. The corpuscles diminished in size as the coloured 

 droplets passed out, while at the same time the crenation disappeared, 

 and the outline of the corpuscles became more or less uneven. The 

 coloured part of the corpuscles often became aggregated into two or 

 three or more rounded masses, causing a projection at those points. 

 The corpuscle thus often had a dumb-bell, triradiate, or stellate 

 form with rounded angles. Very often one or more of these knobs 

 would become pedunculated, and at length break off from the cor- 

 puscle. Sometimes a corpuscle would be seen floating about with 

 several of these coloured globular masses attached to it by long pro- 

 cesses, while but a very small amount of colouring matter remained 



* Preyer, " Virchow's Arcliiv," vol. xxx, p. 432. 



t " Trans. Mic. Soc," vol. xii, N.S., p. 32, and " Quart. Journ. Mic. Sc.," 

 vol. iv, N..S., 1864. 



