100 



THE AMEBIC AN NATURALIST [Vol. L 



ities in the F 2 generation are more frequent than in the F t . 



The fourth section shows the influence on the grand- 

 children of an alcoholized grandfather on the mother's 

 side. This is the most injurious combination shown. 

 Only 36.84 per cent, of the offspring survive. Of the male 

 descendants of an alcoholized maternal grandfather 32.35 

 per cent, died soon after birth, while proportionally many 

 more, or 40.62 per cent., of the female descendants died. 

 In all a total of 63.15 per cent, of the descendants from 

 alcoholized maternal grandfathers died, which is the high- 

 est mortality record obtained. 



Among the grandchildren of alcoholized maternal 

 grandfathers 10.52 per cent, were deformed, a very high 

 proportion. But of the grandsons only 2.64 per cent, 

 were deformed, while almost five times as many, or 12.5 

 per cent., of the granddaughters were grossly deformed. 

 Thus the females of the F 2 generation from a treated 

 maternal grandfather are poorer when considered from 

 the standpoint of mortality record and bodily structure 

 than the male F 2 's from the same source. 



The fifth line to be considered is that of an alcoholized 

 grandmother on the father's side. The result of this 

 treatment as shown by the grandchildren is very bad, but 

 not quite so bad as from the alcoholized maternal grand- 

 father just discussed. 



From alcoholized paternal grandmothers the conditions 

 of 37 grandsons and 33 granddaughters are to be com- 

 pared. About the same survival record is shown by both 

 sexes : 67.56 per cent, of the male grandchildren lived and 

 69.69 per cent, of the females lived. Of all the descend- 

 ants from this combination, including those in which the 

 sex was not determined, only 45.28 per cent, survived, 

 giving a mortality record of 54.71 per cent., considerably 

 better, by almost 10 per cent., than that of animals from 

 an alcoholized maternal grandfather in the preceding 

 section. 



A large proportion of the animals from alcoholized pa- 

 ternal grandmothers were deformed, 10.37 per cent. 

 However, only 5.4 per cent, of the grandsons were de- 



