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THE AMERICAN NATURALIST [Vol. L 



for the teleost heart. At any rate we are aware that once 

 we begin to question further, the necessity of further 

 knowledge becomes evident. This paper can be brought 

 to a close in no better way than by quoting a statement 

 made by Claude Bernard ( '65). We may accept it as one 

 of the laws of evolution and conclude that inquiries con- 

 cerning the osmotic pressures of the blood of animals 

 amply prove its truth. 



Chez tous les etres vivants, le mileau interieur, qui est un produit de 

 l'organisme, conserve des rapports necessaires d'exchanges et d'equilibre 

 avee le mileau cosmique exterieur; mais, a mesure que l'organisme 

 devient plus parfait, le mileau organique se specific et s'isole en quelque 

 sorte de plus en plus du milieu ambiant. 



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