15 



Ihe saliva (Rasmussen 51). Fungi have also been isolaled from Ihe 

 iiasal cavity. Kuster (36) menlions Ihat Renon oblained Aspergilliis 

 famigatus from nasal secretion. Paulsen (49) found several cases 

 of the presence of species of Miicor and Aspergilliis in Ihe nose. 

 ScHUBERT (57) reports a case of stoppage of Ihe nasal passages by 

 ihe vigorous growih of Aspergilliis fiimigatiis, and Hasslauer (25) 

 found three cases of Ihe presence of »Schimmelpilze» in diseased 

 nose. Nasal catarrh has further been claimed by Stoll (61) to 

 result from inhalation of spores of Penicilliiim criistaceiim. 



The ear is also subject to invasions of fungi, but they are in 

 most cases unable to penetrate the epidermis, and the healthy ear 

 is not endangered. Siebenmann (58) met among others, with 

 Aspergilliis fiimigatas, A. niger, A. flaims, A. nidiilans, Mucor, and 

 species of Penicilliiim, and Supfe (62) has recently recorded some 

 not further determined moulds, belonging to the genera Penicillium, 

 Mucor, and Aspergilliis. 



In rare cases the eye becomes diseased due to the attacks of 

 moulds, causing what physicians call keratomycosis. Aspergillus 

 famigatus seems to be the species most commonly reported from 

 diseased eye Plaut (50), but A. nidiilans, A. flavus, and species of 

 Rliizopus have also been met with (Trubin 66). 



Bronchopneumonomycosis or the fungal disease of the lungs and 

 the bronchial tubes, due to the invasion of species of Mucor and 

 Aspergillus is, however, by far the most serious mycosis in man 

 and animals. Renon (52) found that a certain class of people in 

 Paris, employed to feed young pigeons with mouldy grain, taken 

 in the mouth, masticated, and put in the mouths of the birds, 

 suffered severely from pulmonary mycosis strikingly resembling 

 tuberculosis in appearance and effect. He states that Aspergillus 

 fumigatus may play a primary or secondary role in the developmenl 

 of the disease in both man and animals, and considers this species 

 not merely a simple saprophyte but a true parasite. Mohler and 

 BucKLEY (42) have an interesting discussion of pulmonary mycosis 

 in birds and conclude that the lungs, particularly of birds, are 

 veritable propagating houses for A. fumigatus. Numerous additional 

 cases of pneumonomycosis in both man and animals are given by 

 Plaut (50). The experimental phase of the subject has been treated 

 by a number of investigators, which hy injection of spores in- 

 Iraabdominally and intravenously in animals, have conclusively 

 proven the pathogenicity of different species of Mncor and Aspergillus. 



