1904.] Royal Commission on Tuberculosis. 161 



taken to prevent any animal from approaching the carcase or 

 the place where the animal has died until the officers of the 

 Local Authority arrive and prepare for the disposal by burial, 

 or otherwise, of the carcase, without cost to the owner. 



A leaflet, No. 28, on anthrax can be obtained, gratis and post 

 free, from the Board. 



In their Interim Report, which has recently been issued, the 



Commissioners state that the first inquiry undertaken by them 



was to ascertain what were the effects 



Report Of the Royal produced by introducing into the body of 

 Commission on , . , , u . . y r 



Tuberculosis bovine animal tuberculous material of 



human origin, and how far these effects 



resembled or differed from the effects produced by introducing 



into bovine animals, under conditions as similar as possible, 



tuberculous material of bovine origin. Use has been made up 



to the present of more than twenty different " strains " of 



tuberculous material of human origin. In the case of seven of 



these strains the introduction of the human tuberculous material 



into cattle gave rise at once to acute tuberculosis, with the 



development of widespread disease in various organs of the 



body, such as the lungs, spleen, liver, lymphatic glands, &c. In 



some instances the disease was of remarkable severity. 



In the case of the remaining strains, the bovine animal into 



which the tuberculous material was first introduced was affected 



to a less extent. The tuberculous disease was either limited to 



the spot where the material was introduced (this occurred, 



however, in two instances only, and these at the very beginning 



of the inquiry), or spread to a variable extent from the seat of 



inoculation along the lymphatic glands, with, at most, the 



appearance of a very small amount of tubercle in such organs 



as the lungs and spleen. Yet tuberculous material taken from 



the bovine animal thus affected, and introduced successively into 



other bovine animals, or into guinea-pigs from which bovine 



animals were subsequently inoculated, has, up to the present, in 



the case of five of these remaining strains, ultimately given rise 



in the bovine animal to general tuberculosis of an intense 



N 



