i6 



Scientific Proceedings (25). 



not begin before the lapse of six or seven hours. In the rigor 

 after injection of a calcium salt the extensors mostly prevail irre- 

 spective of the original position. After treatment with magnesium 

 salts the flexors prevail or the animal remains in the original 

 position. The degree of the final rigidity after injection of a mag- 

 nesium salt is not less than after similar introduction of calcium. 

 The release from rigor appears earlier after injection of a calcium 

 salt than after similar treatment with a magnesium compound. 

 The administration of curare does not retard the calcium effect but 

 it increases moderately the delaying effect of magnesium. The 

 strong accelerating effect of a developed strychnin tetanus is not 

 interfered with by magnesium. But the tetanus of a strong dose 

 of strychnin can be completely suppressed and then the delaying 

 effect of magnesium remains unimpaired. Calcium salts also 

 hasten the heart rigor and magnesium salts delay it. 



8 (264) 



Restraint and promotion of tumor growth. 

 By SIMON FLEXNER and JAMES W. JOBLING. 



[From the Rockefeller Institute for Medical Research.^ 



At a previous meeting of this society, we reported upon the 

 promoting influence of heated tumor emulsion upon tumor growth 

 in rats. 1 This evening we wish to report briefly the results ob- 

 tained upon the re-inoculation of rats having tumors or having 

 recovered spontaneously from them as affected by the injection 

 of the heated emulsion of tumor cells and other substances. 



The rats were grouped into several series as follows : 



(a) Rats with tumors undergoing spontaneous absorption. 



(b) Rats from which tumors after a degree of growth had dis- 

 appeared spontaneously. 



(c) Rats which failed to develop tumors on primaiy inoculation. 

 At the time these experiments were carried on, the sarcoma 



was at maximum virulence and gave approximately one hundred 

 per cent, of successful implantations. Of these a certain number 

 later underwent retrogression, as always happens with this tumor. 



1 Flexner and Jobling : This journal, 1907, iv, p. 156- 



