Influence of Carbohydrate on Protein Metabolism. 73 



mother dog in both cases. The reduction of the nitrogen elimina- 

 tion on the second sugar day as compared with the fasting day 

 just preceding, was 20 per cent, in the non-pregnant condition 

 instead of 50 per cent, in the pregnant condition. 



Table I. 



Dog Pregnant 9TH Week. 



Date, Dec, 1907. 



Weight, Kgm. 



Carbohydrate. 



Nitrogen in the Urine. 



Total. 



Urea. 



NH, 



Urea+NH, 



Creatinin. 



Creatin. 



Unde- 

 termined. 



■ 



a 



0 



Per Cent. 



Gms. 



Per Cent. 



m 



e 

 a 



Per Cent. 



Gms. 



Per Cent. 



Gms. 



Per Cent. 



Gms. 



Per Cent. 



7 



12.46 



3d day 



S-036 



4.383 



87 



O.I90 



3-7 



4-573 



9O.7 



O.078 



1-5 



O.084 



1.6 



O.30I 



6.2 







fasting. 





2.614 



76.9 









80.4 















8 



12.24 



42 gm. 



3.4OI 



O.I 20 



3-5 



2.834 



O.082 



2.4 



0.I4I 



4-1 



0.344 



I3.I 







cane sugar. 





1.874 





O.058 









O.085 





O.164 



6.5 







9 



I2.IO 



42 gm. 



2-495 



75-1 



2-3 



1.932 



77-4 



34 



0.314 



12.7 







cane sugar. 



(5o% red.) 



























10 



I2.00 



fasting. 



3.240 



2.627 



8l.O 



O.I37 



4-2 



2.764 



85.2 



O.050 



1.5 



0.157 



5-4 



O.269 



7.9 



Table II. 



Same Dog, Four Weeks After Weaning Puppies. 



Date, Feb., 1908. 



Weight, Kgm. 



Carbohydrate. 



Nitrogen in the Urine. 



Total. 



Urea. 



NH 



s 



Urea+NH, 



Creatinin. 



Creatin. 



Unde- 

 termined. 



Gms. 



Per Cent. 



M 



a 



0 



Per Cent. 



Gms. 



Per Cent. 



Gms. 



Per Cent. 



Gms. 



Per Cent. 



Gms. 



Per Cent. 



15 



IO.42 



3d day 



2.856 



2.420 



84.7 



01 33 



4-6 



2.553 



89.3 



O.089 



3-1 



O.O45 



1.6 



O.169 



6.0 







fasting. 



















16 



I0.20 



42 gm. 



2.520 



2.150 



85.3 



0.168 



6.6 



2.318 



91.9 



O.078 



3-i 



0.055 



2.2 



O.069 



2.8 







cane sugar. 



2.284 



























17 



IO.16 



42 gm. 



1.942 



85.O 



0.074 



3-2 



2.ol6 



88.2 



O.080 



3-4 



O.059 



2.5 



O.I29 



5-9 







cane sugar. 



(20% red.) 



















18 



IO.04 



fasting. 



2.352 



1.999 



85-1 



0.084 



3-5 



2.083 



88.6 



O.081 



3-4 



0.040 



1.7 



O.I48 



6-3 



19 



9-82 



fasting. 



2.587 



2.127 



82.2 



0.124] 4.8 



2.251 



87.0 0.081 



3-i 



O.056 



2.2 



O.I99 



7-7 



The greater effect of the sugar in the former experiment is due 

 to a large relative, as well as an absolute, reduction in the urea 

 plus ammonia nitrogen. The explanation might be either that the 

 sugar interfered with the production of urea and ammonia, that 

 is, with deamidization and dehydration of the proteins placed in 

 circulation when fasting is superimposed on the pregnancy, or that 



