Innervation of Blood Vessels of the Intestine. 95 

 56 (312) 



Regarding the innervation of the blood vessels of the intestine. 



By R. BURTON-OPITZ. 



[From the Physiological Laboratory of Columbia University, at the 

 College of Physicians and Surgeons.] 



Quantitative measurements of the blood flow in the mesen- 

 teric vein proved that the innervation of the blood vessels of 

 the intestine by way of the splanchnic nerves is bilateral. Vaso- 

 constrictory effects were produced on stimulation of the left and 

 right splanchnicus major. 



Cutting the cervical parts of the nervi vagi caused a marked 

 slowing of the blood stream. Division of the vagi above the dia- 

 phragm produced a similar but much milder effect. 



The experiments also tend to show that the vagi contain vaso- 

 constrictor)'' fibers for the intestine. 



57 (313) 



Note on anaphylaxis to horse serum. 



By PAUL A. LEWIS. 



\From the Antitoxin Laboratory of the Massaclmsetts State Board 



of Health^ 



Young guinea pigs, bred from mothers which have been 

 treated with a mixture of horse serum and diphtheria antitoxin, 

 are found very susceptible to the toxic action of horse serum. 

 Recently I have had the opportunity to study the blood of these 

 guinea pigs hypersusceptible by reason of their descent and can 

 now contrast its properties with those of the blood of the animals 

 hyper-sensitized by direct treatment. The blood of the animals 

 directly or actively sensitized contains a substance which when 

 the blood is transferred to untreated young animals of normal 

 descent, renders them immediately (within 24 hours) hypersensi- 

 tive to horse serum. It also contains a substance which renders 

 "fresh" animals to which it is transferred hypersensitive, after an 

 incubation period corresponding to that required for direct sensitiza- 

 tion by horse serum. This substance, designated as " anaphy- 



