Pyloric Obstruction on Gastric Secretion. 109 



65 (321) 



The effect of mechanical obstruction of the pyloric outlet on 

 gastric secretion. 



By NELLIS B. FOSTER and ADRIAN V. S. LAMBERT. 



\_From the Laboratory of Biological Chemistry of Columbia Univer- 

 sity, at the College of Physicians and Surgeons .] 



Obstruction at the pylorus was induced in dogs with Pawlow 

 double stomachs, by passing a silver band around the pylorus and 

 regulating the constriction so as to narrow but not entirely oc- 

 clude the pyloric lumen. The effects of this operation upon gas- 

 tric secretion were primarily : (1) A diminution in the amount 

 of gastric juice secreted in the first two hours after taking food, 

 that is, there was a decrease in the amount of appetite juice. (2) 

 The digestive period was much prolonged, a copious secretion 

 continuing into the seventh and eighth hours, when, under normal 

 conditions with the same foods, no secretion took place after the 

 fourth hour. (3) There was a constant secretion of gastric juice 

 without regard to the time of the last feeding and having no ap- 

 parent relation to whether the stomach contained food or was 

 empty, and also (4) a marked hypertrophy of the muscle coats of 

 the stomach at the pyloric end, with moderate dilatation of the car- 

 diac portion. 



66 (322) 



Transplantation of devitalized arterial segments. 



By ISAAC LEVIN and JOHN H. LARKIN. 



\From the Department of Pathology of Columbia University, at the 

 College of Physicians and Surgeons. ,] 



Before entering upon the discussion of the subject matter, we 

 will take this opportunity to pay our tribute to the pioneer in the 

 surgery of blood vessels. On the eighteenth of last April, Dr. 

 N. V. Eck died in St. Petersburg. Nearly a decade ago he suc- 

 ceeded in uniting the portal vein to the cava in a dog, thus per- 

 forming the operation for the Eck fistula. 



Carrel demonstrated that it is not only possible to unite the 

 two ends of a severed artery by a circular suture, but also to in- 

 terpose between the cut ends a segment of an artery of another 



