Scientific Proceedings. 



(211) 41 



0.071 gm. per day. The exact nature of the nitrogenous material 

 thus excreted was not studied. A number of experiments were 

 made on a professional bicycler, riding a bicycle ergometer. The 

 exercise was very severe, as the total output of heat was 600 

 calories per hour. The bath water and the extract water from the 

 clothing gave a total of 0.87 gm. in a 4-hour experiment, or 0.22 

 gm. of nitrogen per hour. 



Of greatest significance is the important bearing of this channel 

 for the excretion of nitrogenous material in experiments on the 

 metabolism of protein. Profuse perspiration, whether induced 

 passively or by muscular work, results in a considerable excretion 

 of nitrogenous material through the skin. While the work engaged 

 in by the subjects of these experiments was severe, certainly that of 

 some of them was not extraordinarily so, and might well be equaled 

 by many men engaged in ordinary occupations involving muscular 

 work. A total excretion equivalent to one or more grams of 

 nitrogen per day is not at all inconsiderable, and hence in accurate 

 metabolism experiments we must give recognition to the possibility 

 of excretion through this hitherto almost unconsidered channel. 

 Especially is this so in experiments where the total amounts of 

 nitrogen in the ingesta and egesta are smaller than normal, since 

 the percentage error is thereby proportionally larger. 



20 (112). " The effects of intravenous injections of solutions of 

 dextrose upon the viscosity of the blood " : RUSSELL BUR- 

 TON-OPITZ. 



The experiments were performed upon dogs, in accordance 

 with the method devised by Hurthle. When small quantities 

 (5 c.c.) of a concentrated solution of dextrose were injected intraven- 

 ously, the viscosity of the blood became slightly greater. By the 

 administration of large quantities (50 c.c. to 100 c.c.) the viscosity 

 was markedly decreased at first, but reassumed its normal value in 

 the course of about one hour. 



By producing artificial glycosuria, the viscosity was decidedly 

 increased. In the latter series of experiments the surface of the 

 pancreas was painted with solution of adrenalin. The specific 

 gravity of the blood pursued in all cases a harmonious course with 

 the viscosity. 



