Scientific Proceedings. ( 22 9) 59 



Table I. — Amounts of Glycogen in the Livers of Control Rabbits. 



Exp. No. 



Kabbit Wt. 



Liver Wt. 



Food 

 Before 

 Fasting. 



Fasting 

 Period. 



Treatment 

 During 

 Fasting. 



Hepatic • 

 Glycogenj 

 Per cent. 



I 



820 gms. 



22 gms. 



C. H. O.i 



4 days 



* i 



None 



2 



1320 " 



4 I " 



<« «< << 



5 " 





«« 



5 



1 230 ' 1 



27 " 



Carrots 3 days 



5 " 





0.139 



6 



970 « 



22 " 



<< tt 



5 " 



"So -g 



0. 148 



8 



1370 " 



42 » 



tt tt 



6 " 



£ a 



0.043 



IO 



1265 " 



38 « 





4 " 





0.127 





1470 » 



53 " 



<< <« 



4 " 





None 



Table II. — Amounts of Glycogen in the Livers of Rabbits after Ad- 

 ministration of Alcohol. 



Exp. No. 



Rabbit Wt. 



Liver Wt. 



Food 

 Before 

 Fasting. 



Fasting 

 Period. 



Alcohol Per 

 Kilo. Daily. 



Hepatic 

 Glycogen 

 Per cent. 



I A 



1 120 gms. 



48 gms. 



C. H. O.i 



4 days 



ioc.c. 30 per cent. 



None 



2 A 



1 100 " 



35 " 



<< t« «« 



5 " 



IOC.C. " 





5 A 



1 100 " 



44 " 



Carrots 3 days 



5 " 



IOC.C. " 



0.8 



6 A 



1300 " 



48 " 



<« << 



5 " 



IOC.C. " 



0.28 



9 



1280 " 



47 " 



<« a 



6 " 



IOC.C. " 



Trace 



7 A 



1500 " 



53 " 



U 



6 



IOC.C. " 



0.083 



9 A 



1270 " 



43 " 



(« «( 



6 " 



IOC.C. " 



Trace 



10 A 



1470 " 



53 4< 





4 " 



IOC.C. " 



0.018 



11 A 



i35o " 



54 " 



<« «< 



4 " 



IOC.C. " 



0. 148 



17 A 



1800 " 



66 " 



Carrots 4 days 

 «< << 



3i" 

 4 " 



I2c.c. 60 per cent. 



None 



18 A 



1130 " 



45 " 



15C.C. " 



None 



19 A 



800 " 



35 " 



C. H. 0. 



4 4< 



I2C.C. " 



Trace 



mation of glycogen de novo does not take place, under the influence 

 of alcohol, a number of experiments were carried out to ascertain 

 whether alcohol retards the disappearance of glycogen from the 

 liver during fasting. 



To test this point rabbits were brought up to a maximum of gly- 

 cogen accumulation by feeding carrots for 3 days. Alcohol (10 c.c. 

 of 30 per cent, per kilo) was then given in the way already stated, 

 for 4, 5 or 6 days. As may be seen on inspecting Table II the results 

 were negative. In one experiment only was an appreciable amount 

 of glycogen found. In the rest of the experiments the amounts of 

 glycogen obtained in alcohol fed rabbits were about the same as in 

 the controls. In this connection it might be mentioned that the 

 amount of glycogen found in rabbits killed after feeding carrots 

 for three days varied between 4 and 7 per cent. Larger quantities 

 of stronger alcohol were then tried. The administration of 1 2 to 

 15 c.c. of 60 per cent, alcohol per kilo daily for 4 days, after bring- 



iC. H. O.— Cabbage, Hay, Oats. 



