Anaphylactic Reaction. 



67 



In the immune guinea-pig, or guinea-pig that has received 

 multiple injections of the foreign protein, the cellular hypersen- 

 sitiveness is usually greater than that of the 4-week anaphylactic 

 guinea-pig. A bronchial spasm, however, is prevented by the 

 inhibiting and protective action of the immune blood elements. 



In the immune guinea-pig, therefore, we have a paradoxical 

 phenomenon, the coexistence of a cellular anaphylaxis and a 

 humoral immunity. A removal or reduction of the humoral im- 

 munity leads to a fatal bronchial spasm in the immune guinea-pig. 



