Absorption of Foreign Protein by Anaphylactic Lungs. 129 



tinctly resistant. The blood prevents the reaction if mixed with 

 anaphylactic blood. 



( / ) Humoral anaphylaxis and humoral immunity. This third 

 seeming paradox is illustrated by the blood of partially immunized 

 rabbits, which contains a thermo-labile anaphylactic substance, 

 partially inhibited by a thermo-stable antitoxin. 



77 (1255) 



Absorption of foreign protein by the anaphylactic lungs. 



By W. H. Manwaring and Harold E. Crowe. 



[From the Department of Bacteriology and Experimental Pathology, 

 Leland Stanford Jr. University.] 



If the lungs of an anaphylactic guinea pig are repeatedly 

 perfused with dilute foreign protein, either in Locke's solution or 

 in 50 per cent, normal blood, the lungs are thrown into a typical 

 anaphylactic response. 



Quantitative titrations of the perfusion fluid, by means of a 

 specific precipitating serum, show no recognizable changes in the 

 amount of protein as a result of the repeated passages through the 

 lungs. 



The titrations therefore furnish no support, either for the 

 sessile receptor hypothesis of Ehrlich, or for the protein-destruction 

 theory of Vaughan. 



