Scientific Proceedings (35). 



practically the same in both normal and tetany dogs. The calcium 

 and magnesium content of the feces of normal and parathyroi- 

 dectomized dogs is similar. During fasting, the excretion of both 

 metals is diminished. The excretion of magnesium, in the urine, 

 in dogs on a constant diet, as well as in those fasting, runs parallel 

 with that of calcium. The excretion of both metals is markedly 

 diminished during fasting. After parathyroidectomy with the 

 animal fasting, the elimination of magnesium is greatly increased, 

 while that of calcium remains unchanged. The augmentation of 

 the magnesium begins before tetany is observed. This increased 

 elimination of magnesium indicates that although there is a dis- 

 turbance of inorganic equilibrium, it is not limited to calcium. It 

 is suggested that the tetany represents a condition of altered salt 

 equilibrium in the nerve cells brought about by a disturbance in 

 the catalytic processes of the body which increases the acid factors. 



10 (420) 

 Non-fixation of complement. 



By HIDEYO NOGUCHI. 



\From the Laboratories of the Rockefeller Institute for Medical 



Research^ 



With a view of obtaining an antihuman hemolytic amboceptor 

 on a large scale, I immunized a goat with thoroughly washed 

 human corpuscles. I obtained a serum of a titre of 0.0 1 cubic 

 centimeter, that is, capable of complete hemolysis with 1 cubic 

 centimeter of a one per cent, suspension of washed human cor- 

 puscles in the presence of 0.0 1 cubic centimeter of normal goat's 

 or guinea-pig's serum. The reactivating property of normal goat's 

 serum for this ambocepter was found to be somewhat superior to 

 that of guinea-pig's complement. As it would be of great econom- 

 ical value for complement fixation tests to utilize an amboceptor 

 and complement from such a large animal as a goat, instead of 

 using an amboceptor from rabbits and complement from guinea- 

 pigs, I tested the amboceptor and complement from goats as to 

 the possibility of using them in complement fixation tests in gen- 

 eral. // was soon found that no complement-fixation phenomenon 

 can be obtained by using them (antihuman amboceptor from this im- 



