Eefect of Anemia on Hyperplastic Goitre. 



45 



As previously reported {Jour, of the American Med. Assoc., 1908, 

 li, 1658), the cat did not survive the functional test (removal of 

 the remaining original kidney) made over a year later. 



Results. — Structurally, the engrafted kidney was very fibrous. 

 Histologically, a reminiscence only of normal renal structure 

 remained, it being possible only with care to trace the glomeruli 

 and the beginning of the tubular structures. 



28 (438) 



The effect of anemia and of double hyperemia on hyperplastic 



goitre. 



By 0. C. GUTHRIE. 



[From the Physiological Laboratories of Washington and Pittsburgh 



Universities.] 



In a dog showing a bilaterally symmetrical hyperplastic goitre, 

 Dog 16, the following vascular changes were made : 



A. Anemia, left side : 



1 . Ligation of the left common carotid and superior thyroid 

 arteries. 



B. Double hyperemia, right side : 



1. Ligation of the internal jugular vein below the mouth 



of the inferior thyroid vein and above the superior 

 thyroid vein (passive hyperemia). 



2. Section of the internal jugular vein below the origin of 



inferior thyroid vein and anastomosis of the distal end 

 to the central end of the left common carotid artery. 

 Results. — Clinically, on the left side (anemic), no marked 

 change was observed. On the right side (hyperemic), a great tem- 

 porary swelling followed by a marked decrease in size of the right 

 lobe occurred. Seven months later the left lobe measured 8 by 

 4.5 by 3 centimeters, and the right lobe measured 5 by 2.5 by 2 

 centimeters. 



Structurally, the right lobe was more fibrous than the left and 

 there appeared to be present a larger proportion of normally stain- 

 ing colloid. 



