8o 



Scientific Proceedings (36). 



46 (456) 



Remote results of the replantation of the kidneys. 



By ALEXIS CARREL. 



[From the Laboratories of the Rockefeller Institute for Medical 



Research^ 



When a kidney is extirpated from an animal and replanted on 

 the same animal with a proper technique, it does not undergo any 

 anatomical or physiological changes. In several cases, I exam- 

 ined a kidney several months after its extirpation and replantation 

 and could not detect any anatomical change. Ten months after 

 the resection and the replantation of the left kidney of a dog, 

 the organ was examined. Its size and appearance were identical 

 to those of the right kidney. The vascular and ureteral anasto- 

 mosis were almost invisible. There were no microscopical differ- 

 ences between the kidneys. 



Two years ago, a bitch underwent a double nephrectomy and 

 the replantation of the left kidney. Since that time she has be- 

 come pregnant twice, has had a number of normal pups, and is 

 still in perfect health. 



These experiments show that, from a surgical standpoint, the 

 question of the graft of organs is solved. The bad results obtained 

 by some experimenters are due merely to faults of technique. 



47 (457) 



Temporary diversion from the left ventricle to the 

 descending aorta. 

 By ALEXIS CARREL. 



In the plastic operations on the thoracic aorta, it is necessary 

 not to interrupt the circulation for a long time. Therefore, the 

 blood must be diverted. I described already the central diversion 

 of the blood by intubation of the aorta. I attempted also to 

 established a communication between the left ventricle and the 

 descending aorta, by means of a paraffined rubber tube or a vein 

 preserved in cold storage. I succeeded twice to direct the blood 

 directly from the heart into the descending aorta. The ascending 

 aorta was then clamped, and the circulation reversed through the 

 upper part of the descending aorta. 



The purpose of these experiments is to develop a technique 

 permitting operations on the first part of the arch of the aorta. 



