104 



Scientific Proceedings (38). 



On the basis of this conception, several series of experiments 

 were carried out to determine, if possible, whether sensitization by 

 the serum affected the vagus endings in the bronchial muscles, 

 the muscles directly, or both structures. The experiments were 

 carried out by sectioning one vagus in the neck, for according to 

 Dixon and Brodie, the vagus of one side supplies the lung of that 

 side only ; moreover there is no evidence of a cell station between 

 the pulmonary vagus fibers in the neck and bronchial muscle. 



This report deals with only a part of the investigation. In one 

 series of guinea-pigs, one vagus was resected in the neck thirteen 

 days after the sensitizing dose of horse serum had been injected. 

 The toxic dose was given intravenously from 30 to 57 days after 

 vagus section. All of the nine pigs died with typical symptoms 

 within five minutes after injection of the toxic dose. The lungs 

 showed the characteristic picture of inspiratory immobilization on 

 excision, and there was no characteristic difference between the 

 innervated and non-innervated side. 



In another series, one vagus was resected fifty-five days after 

 the sensitizing dose, and the toxic dose was injected intravenously 

 from 6 to 14 days after vagus section. These animals differed in 

 no way from those of the other series. 



In a final series one vagus was resected in normal animals. 

 These experiments are not yet completed and will be reported 

 later. 



From the data given above it seems clear that the bronchial 

 muscles themselves are sensitized by the horse serum in anaphy- 

 laxis. 



65 (475) 



Notes on the vaso-reaction in dogs produced by injections of 

 extracts of the tubercle bacillus. 



By J. P. ATKINSON and CHARLES B. FITZPATRICK. 



[From the Chemical and Research Laboratories of the Department 

 of Health, City of New York.~\ 

 This paper is a report of results in continuation of those read 

 at the February meeting. Of especial interest are the results 

 obtained with the blood serum of three tubercular calves which 

 showed very slight lesions at autopsy. We obtained results 



