Origin of Immune Bodies by Organ Transplantation. 123 



may happen when the macerated "immune" spleen is introduced 

 into the peritoneal cavity of a normal dog. The splenic cells may 

 escape death and give rise to the antibodies in the second dog ; 

 or the antigen may be split off again on the death of splenic cells 

 (on Ehrlich's conception of antigen fixation) and reaching the cir- 



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culation may again attach itself to suitable receptor and thus 

 stimulate to specific antibody production. 



With this method the spleen has given results so striking that 

 I shall include the specific agglutinin curve of a single experiment 

 on a dog which had received intraperitoneally emulsified spleen of 

 another dog immunized 24 hours previously with an intravenous 



