Scientific Proceedings. 



5 



at practically the normal rate. In the absence of impulses through 

 the vagi and in the presence of impulses through the splanchnics 

 the discharge of both carbohydrate and protein is notably retarded. 

 But this retardation, especially when protein is fed, is much more 

 marked soon after the operation than it is later. Again a distinc- 

 tion must be drawn between the immediate depressing effect of 

 vagus section and the later considerable recovery of normal func- 

 tioning. Although the passage of both carbohydrate and protein 

 from the stomach remains slower after vagus section, the charac- 

 teristic treatment of the two food-stuffs persists — the carbohy- 

 drate passes out much more rapidly than the protein food. 



When all extrinsic nerves have been cut there is, as in the cases 

 of vagus section alone, a difference between the immediate defect 

 and the later partial recovery of normal function. After recovery, 

 the carbohydrate passes the pylorus at about the same rate as 

 when vagi alone are cut, but the protein discharge is more nearly 

 normal when all nerves are cut than when vagi alone are severed. 

 After all splanchnic and vagus impulses are removed a character- 

 istic difference between the outgo of carbohydrate and the outgo 

 of protein food from the stomach is still maintained. 



Passage of food through the small intestine. — After splanchnic 

 section the rate of transit from pylorus to ileocolic sphincter, when 

 protein was fed, was much accelerated, and after vagus section it 

 was much slower than normal. The rate was slower also when all 

 nerves were cut. The variation from the normal was in all cases 

 less with carbohydrate food than with protein. 



Rhythmic segmentation of the food in the small intestine was 

 observed in every condition of nerve section. 



The persistence of characteristically different rates of discharge 

 of protein and of carbohydrate food through the pylorus, after 

 splanchnic section, after vagus section, and after severing both sets 

 of nerves in the same animal, definitely proves that the control of 

 this differential discharge is local and not mediated through the 

 central nervous system. 



